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A dietary antioxidant supplementation of Jamaican cherries (Muntingia calabura L.) attenuates inflammatory related disorders

Food Science and Biotechnology volume 22, pages 787–794 (2013)Cite this article

Abstract

The polyphenolic extract from Jamaican cherries (Muntingia calabura L.) was screened for its antioxidant and anti-inflammatory activities. The extract contained considerable amounts of vitamin C (33.6 mg AAE/g extract) and E (14.7 mg TE/g extract), total phenolics (121.1 mg GAE/g extract), flavonoids (173.2 mg RE/g extract), and anthocyanins (82.4 mg CGE/g extract) estimated through standard spectrophotometric methods. The extract also revealed the presence of volatile compounds such as phytol (26.26%), n-hexadecanoic acid (11.97%), cyclopropaneoctanoic acid (10.26%), γ-sitosterol (11.15%), stigmasterol (7.20%), and campesterol (4.47%) as main constituents in the extract. The polyphenol extract demonstrated DPPH radical scavenging activity (IC50 10.6±0.6 μg/mL) and effectively inhibited hydroxyl (IC50 24.9±3.3 μg/mL), and nitric oxide (IC50 15.01±1.2 μg/mL) radicals in vitro. The extract also exhibited anti-inflammatory activity in a dose dependent manner by significantly (p<0.01) inhibiting carrageenan induced paw edema and reducing the weight of granuloma in cotton pellet-induced granuloma model in rats. Results indicated that Jamaican cherries could be a potential source of nutrient supplement with anti-inflammatory and antioxidant properties and require promotion of their consumption for public health benefits.

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Authors and Affiliations

  1. Department of Life Science, Manian Institute of Science and Technology, Coimbatore, 641 004, Tamil Nadu, India

    Nagarajan Anusuya

  2. Department of Botany, School of Life Sciences, Bharathiar University, Coimbator, 641 046, Tamil Nadu, India

    Rajkumar Gomathi & Sellamuthu Manian

Authors
  1. Rajkumar Gomathi
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  2. Nagarajan Anusuya
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  3. Sellamuthu Manian
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Correspondence to Nagarajan Anusuya.

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Gomathi, R., Anusuya, N. & Manian, S. A dietary antioxidant supplementation of Jamaican cherries (Muntingia calabura L.) attenuates inflammatory related disorders. Food Sci Biotechnol 22, 787–794 (2013). https://doi.org/10.1007/s10068-013-0146-1

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  • DOI: https://doi.org/10.1007/s10068-013-0146-1

Keywords

  • Muntingia calabura
  • polyphenol
  • antioxidant
  • anti-inflammatory
  • carrageenan