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Effect of Dongchunghacho rice on blood glucose level, lipid profile, and antioxidant metabolism in streptozotocin-induced diabetic rats

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Abstract The aim of this study was to investigate the effect of dongchunghacho rice [polished rice cultivated with Paecilomyces tenuipes (PT) or Cordyceps militaris (CM)] on blood glucose level, lipid profile, and antioxidant metabolism in streptozotocin (STZ)-induced diabetic rats. Results of the oral glucose tolerance test showed a significant decrease in the area under the curve value of dongchunghacho rice-supplemented groups compared with that of the diabetic control (DC) group. Total plasma cholesterol significantly decreased in dongchunghacho rice-supplemented groups compared with those of the DC groups. Dongchunghacho rice treatment also markedly increased the erythrocyte superoxide dismutase. Fasting blood glucose exhibited a significant negative correlation with total radical trapping antioxidant potential (TRAP) (r= −0.509, p=0.003) and a significant positive correlation with CD levels (r= −0.498, p=0.004). These results suggest that a 13.6% of dongchunghacho rice supplementation to polished rice has hypoglycemic, hypocholesterolemic, and antioxidant potential in STZ-induced diabetic rats.

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Authors and Affiliations

  1. Department of Food and Nutrition, Kyungnam University, Changwon, Gyeongnam, 631-701, Korea

    Jee-Hee Park & Eunju Park

  2. College of Natural Resources and Life Science, Pusan National University, Miryang, Gyeongnam, 627-130, Korea

    Nam Sook Park & Sang Mong Lee

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  1. Jee-Hee Park
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  2. Nam Sook Park
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Correspondence to Eunju Park.

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Park, JH., Park, N.S., Lee, S.M. et al. Effect of Dongchunghacho rice on blood glucose level, lipid profile, and antioxidant metabolism in streptozotocin-induced diabetic rats. Food Sci Biotechnol 20, 933 (2011). https://doi.org/10.1007/s10068-011-0129-z

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