Abstract:
Wegener’s granulomatosis (WG) is a systemic granulomatous vasculitis that typically affects the upper airways, lungs and kidneys. Lymphadenopathy is rare in patients with WG. Here, we present the first case of WG whose initial manifestation was superficial lymphadenopathy (i.e. supraclavicular and axillary lymphadenopathy). One year after the initial presentation, a mass appeared in the lung. Biopsy specimens obtained from supraclavicular lymph nodes and lung demonstrated granulomatous vasculitis. This patient was negative for classic antineutrophil cytoplasmic antibodies (c-ANCA). Treatment with glucocorticoids, cyclophosphamide and trimethoprim-sulfamethoxazole has induced complete remission.
Similar content being viewed by others
Author information
Authors and Affiliations
Additional information
Received: 11 February 2002 / Accepted: 29 April 2002
Correspondence and offprint requests to: Dr Toshihiko Hashizume, 4-33 Koyo-cho, Miura-City, Kanagawa, 238-0222, Japan. Tel: 81-468-82-2111; Fax: 81-468-81-0225; E-mail: toshi@yk9.so-net.ne.jp
Rights and permissions
About this article
Cite this article
Hashizume, T., Yamaguchi, T. & Matsushita, K. Supraclavicular and Axillary Lymphadenopathy as the Initial Manifestation in Wegener’s Granulomatosis . Clin Rheumatol 21, 525–527 (2002). https://doi.org/10.1007/s100670200128
Issue Date:
DOI: https://doi.org/10.1007/s100670200128