Abstract
The patient presented to the clinic with painful muscle swelling in the right lower extremity, which improved with immunosuppressive therapy. Initially, the condition was diagnosed as polymyositis but recurred soon after. After imaging and biopsy, the final diagnosis was primary skeletal muscle peripheral T-cell lymphoma, not otherwise specified (PSM-PTCL, NOS). In this report, we discuss the challenges in diagnosing and treating this aggressive malignancy and review the literature on PSM-PTCL, NOS.
Key Points • To date, there are few reports of PSM-PTCL, NOS, and our case is the tenth. • It is crucial to consider PSM-PTCL, NOS, when presenting with localized muscle edema and unexplained pain. • Histopathological examination is likely the most effective method for diagnosing this rare disease. |
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References
Murphey MD, Kransdorf MJ (2016) Primary musculoskeletal lymphoma. Radiol Clin N Am 54:785–795. https://doi.org/10.1016/j.rcl.2016.03.008
Bowzyk AA, Ajithkumar T, Behan S, Hodson DJ (2018) Non-Hodgkin lymphoma. BMJ-Br Med J 362:k3204. https://doi.org/10.1136/bmj.k3204
Iizuka H, Harada S, Iwao N, Koike M, Noguchi M (2021) Primary skeletal muscle peripheral T-cell lymphoma: an autopsy case report and review of the literature. Intern Med 60:3309–3315. https://doi.org/10.2169/internalmedicine.7391-21
Hou WH, Zhou XG, Xie JL, Zheng YY, Zhang YL, Wang X (2021) Clinicopathological features and prognosis of the skeletal-muscle cytotoxic T-cell lymphoma. Zhonghua Bing Li Xue Za Zhi. 50:1246–1251. https://doi.org/10.3760/cma.j.cn112151-20210602-00403
Binici D, Karaman A, Timur O, Tasar P, Sanibas AV (2018) Primary skeletal muscle lymphoma: a case report. Mol Clin Oncol 8:80–82. https://doi.org/10.3892/mco.2017.1483
Ashton C, Paramalingam S, Stevenson B, Brusch A, Needham M (2021) Idiopathic inflammatory myopathies: a review. Intern Med J 51:845–852. https://doi.org/10.1111/imj.15358
Dourado E, Bottazzi F, Cardelli C, Conticini E, Schmidt J, Cavagna L, Barsotti S (2023) Idiopathic inflammatory myopathies: one year in review 2022. Clin Exp Rheumatol 41:199–213. https://doi.org/10.55563/clinexprheumatol/jof6qn
Bohan A, Peter JB (1975) Polymyositis and dermatomyositis (first of two parts). N Engl J Med 292:344–347. https://doi.org/10.1056/NEJM197502132920706
Bohan A, Peter JB (1975) Polymyositis and dermatomyositis (second of two parts). N Engl J Med 292:403–407. https://doi.org/10.1056/NEJM197502202920807
Lundberg IE, Tjarnlund A, Bottai M, Werth VP, Pilkington C, Visser M, Alfredsson L, Amato AA, Barohn RJ, Liang MH et al (2017) 2017 European league against rheumatism/American College of Rheumatology classification criteria for adult and juvenile idiopathic inflammatory myopathies and their major subgroups. Ann Rheum Dis 76:1955–1964. https://doi.org/10.1136/annrheumdis-2017-211468
Rieux-Laucat F, Kanellopoulos JM, Ojcius DM (2021) Scaling the tips of the ALPS. Biomed J 44:383–387. https://doi.org/10.1016/j.bj.2021.08.002
Palmisani E, Miano M, Grossi A, Lanciotti M, Lupia M, Terranova P, Ceccherini I, Montanari E, Calvillo M, Pierri F et al (2023) Autoimmune lymphoproliferative syndrome (ALPS) disease and ALPS phenotype: are they two distinct entities? Hemasphere 7:e845. https://doi.org/10.1097/HS9.0000000000000845
Oliveira JB, Bleesing JJ, Dianzani U, Fleisher TA, Jaffe ES, Lenardo MJ, Rieux-Laucat F, Siegel RM, Su HC, Teachey DT et al (2010) Revised diagnostic criteria and classification for the autoimmune lymphoproliferative syndrome (ALPS): report from the 2009 NIH International Workshop. Blood. 116:e35–e40. https://doi.org/10.1182/blood-2010-04-280347
Loudini N, Glaudemans A, Jutte PC, Suurmeijer A, Yakar D, Kwee TC (2019) The diagnostic significance of repeat ultrasound-guided biopsy of musculoskeletal soft-tissue lesions with initially inconclusive biopsy results. EJSO 45:1266–1273. https://doi.org/10.1016/j.ejso.2019.01.185
Surov A (2014) Imaging findings of skeletal muscle lymphoma. Clin Imaging 38:594–598. https://doi.org/10.1016/j.clinimag.2014.03.006
Gao S, Shu H, Yang H (2021) Imaging features of skeletal muscle lymphoma: a case report and literature review. BMC Med Imag 21:136. https://doi.org/10.1186/s12880-021-00667-4
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Zhengyi Jin, Jiaqi Hu, and Thumon Min contributed equally to this work and should be considered co-first authors.
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Jin, Z., Hu, J., Min, T. et al. Myositis as a prominent manifestation of primary skeletal muscle peripheral T-cell lymphoma: a case report and literature review. Clin Rheumatol (2024). https://doi.org/10.1007/s10067-024-07003-5
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DOI: https://doi.org/10.1007/s10067-024-07003-5