Skip to main content

Advertisement

Log in

Lessons and pitfalls from the 2020 Gout Clinical Practice Guideline presented in Atlanta at the ACR 2019

  • Perspectives in Rheumatology
  • Published:
Clinical Rheumatology Aims and scope Submit manuscript

Abstract

Gout is the most common type of arthritis and is evoked by arousal of the inflammasome in the presence of urate crystals superponed on a dysmetabolism with urate accumulation. Gout can be cured in most patients but still treatment is suboptimal in the majority of patients. Quality guidelines for management from experts such as from American College of Rheumatology aim to give guidance to US physicians and their own rheumatologists but have a value worldwide. We should know about the updates that were recently made publicly, with their strong and conditional recommendations, as we may learn and improve from their updated guideline.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. De Meulemeester M, Jansen TL, Petersen G, Perez-Ruiz F (2019) European patient voice in gout survey – subjective satisfaction in gout patients versus objective suboptimal gout care. ARD 78(S2):153–154

    Google Scholar 

  2. De Meulemeester M, Mateus E, Wieberneit-Tolman H et al (2020) Understanding the patient voice in gout: a quantitative study conducted in Europe. BJGP open. https://doi.org/10.3399/bjgpopen20X101003

  3. Richette P, Clerson P, Perissin L, Flipo RM, Bardin T (2015) Revisiting comorbidities in a gout: a cluster analysis. ARD 74:142–147

    PubMed  Google Scholar 

  4. Richette P, Doherty M, Pascual E, Barskova V, Becce F, Castañeda-Sanabria J, Coyfish M, Guillo S, Jansen TL, Janssens H, Lioté F, Mallen C, Nuki G, Perez-Ruiz F, Pimentao J, Punzi L, Pywell T, So A, Tausche AK, Uhlig T, Zavada J, Zhang W, Tubach F, Bardin T (2017) 2016 updated EULAR evidence-based recommendations for the management of gout. ARD 76:29–42. https://doi.org/10.1136/annrheumdis-2-16-209707

    Article  CAS  PubMed  Google Scholar 

  5. Bardin T, Keenen RT, Khanna PP et al (2017) Lesinurad in combination with allopurinol: a randomised, double-blind, placebo-controlled study in patients with gout with inadequate response to standard of care (the multinational CLEAR 2 study). ARD 76:811–820. https://doi.org/10.1136/annrheumdis-2016-209213

    Article  CAS  PubMed  Google Scholar 

  6. Saag KG, Fitz-Patrick D, Kopicko J et al (2016) Lesinurad combined with allopurinol: randomized, double-blind, placebo-controlled study in gout subjects with inadequate response to Standard of Care Allopurinol. Arthritis & Rheumatol. https://doi.org/10.1002/art.39840

    Article  Google Scholar 

  7. Dalbeth N, Jones G, Terkeltaub R, Khanna D, Fung M, Baumgartner S, Perez-Ruiz F (2019) Efficacy and safety dering extended treatmentof lesinurad in combination with febuxostat in patients with tophaceous gout: CRYSTAL extension study. ART 21:8. https://doi.org/10.1186/s13075-018-1788-4

    Article  Google Scholar 

  8. Neogi T, Jansen TL, Dalbeth N, Fransen J, Schumacher HR, Berendsen D, Brown M, Choi H, Edwards NL, Janssens HJ, Lioté F, Naden RP, Nuki G, Ogdie A, Perez-Ruiz F, Saag K, Singh JA, Sundy JS, Tausche AK, Vaquez-Mellado J, Yarows SA, Taylor WJ (2015) 2015 gout classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. ARD 74:1789–1798

    CAS  PubMed  Google Scholar 

  9. Richette P, Doherty M, Pascual E et al (2019) 2018 updated EULAR evidence-based recommendations for the diagnosis of gout. ARD. https://doi.org/10.1136/annrheumdis-2019-215315

    Article  Google Scholar 

  10. Doherty M, Jenkins W, Richardson H et al (2018) Efficacy and cost-effectiveness of nurse-led care involving education and engagement of patients and a treat-to-target urate-lowering strategy versus usual care for gout: a randomised controlled trial. Lancet 392:1403–1412

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Tim L. Jansen.

Ethics declarations

Disclosures

None.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Jansen, T.L., Janssen, M. Lessons and pitfalls from the 2020 Gout Clinical Practice Guideline presented in Atlanta at the ACR 2019. Clin Rheumatol 39, 2011–2016 (2020). https://doi.org/10.1007/s10067-020-05070-y

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10067-020-05070-y

Keywords

Navigation