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Hypertension is associated with increased age at the onset of psoriasis and a higher body mass index in psoriatic disease

Clinical Rheumatology volume 38, pages 2063–2068 (2019)Cite this article

Abstract

Background and aims

High blood pressure (HBP) is a common comorbidity in psoriatic disease. Some studies indicate a higher prevalence of HBP among arthritis patients, in relation to psoriasis alone, within the psoriatic spectrum. Our objective was to study the prevalence of HBP in both types of patients as well as to analyse the factors associated with it.

Methods

A cross-sectional observational study of 600 patients with psoriatic disease attended in a multidisciplinary clinic of a reference centre. We first analysed the frequency of this comorbidity and then the factors associated with it using conditional logistic regression. The significant factors in this first model were introduced in a multivariate model using a backward step approach.

Results

A total of 144 patients were hypertensive (24%). Of patients with arthritis, 86/290 (29.7%) had HBP, compared with 58/310 (18.7%) with psoriasis (OR 1.7 95%, CI 1.25–2.50, p = 0.003). Hypertension was independently associated with higher age at onset of psoriasis (OR 1.04, 95%CI 1.03–1.06, p < 0.001) and a higher body mass index (OR 1.13, 95%CI, 1.06–1.22, p < 0.001).

Conclusions

HBP is more prevalent in patients with arthritis within the spectrum of psoriatic disease. Patients with a higher body mass index and those with later-onset psoriasis are more prone to this comorbidity.

Key Points

• The factors of psoriatic disease associated with HBP are little known.

• HBP is more prevalent in patients with arthritis within the spectrum of psoriatic disease.

• In patients with psoriatic disease, for each point of increase in the body mass index, the risk of HBP increases by 13%.

• For each year of onset of psoriasis above 40 years, the risk of HBP increases by 4%.

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Authors and Affiliations

  1. Rheumatology Division, Hospital Universitario Central de Asturias (HUCA), Avda de Roma s/n, 33011, Oviedo, Spain

    Rubén Queiro, Andrés Lorenzo, Patricia Tejón & Estefanía Pardo

  2. Dermatology Division, Hospital Alvarez Buylla, Mieres, Asturias, Spain

    Pablo Coto

Authors
  1. Rubén Queiro
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  2. Andrés Lorenzo
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  3. Patricia Tejón
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  4. Estefanía Pardo
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  5. Pablo Coto
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Correspondence to Rubén Queiro.

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Queiro, R., Lorenzo, A., Tejón, P. et al. Hypertension is associated with increased age at the onset of psoriasis and a higher body mass index in psoriatic disease. Clin Rheumatol 38, 2063–2068 (2019). https://doi.org/10.1007/s10067-019-04519-z

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  • DOI: https://doi.org/10.1007/s10067-019-04519-z

Keywords

  • Comorbidity
  • High blood pressure
  • Psoriasis
  • Psoriatic arthritis