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Table 3 Comparison of various parameters in patients before and after treatment in both groups

From: Leflunomide versus cyclophosphamide in the induction treatment of proliferative lupus nephritis in Chinese patients: a randomized trial

  LEF CTX
  Before treatment After treatment Before treatment After treatment
Proteinuria (g/day) 3.89 (1.46~5.48) 0.86 (0.18~1.74)** 3.63 (2.01~6.90) 0.50 (0.16~1.18)**
Serum albumin (g/L) 26.69 ± 8.70 40.18 ± 7.47** 26.58 ± 8.05 39.01 ± 7.05**
Serum creatinine (μ mol/L) 63.4 (51.6–104.8) 60.0 (53.1–69.5) 71.3 (56.8–84.0) 61.3 (53.9–75.0)
Anti-dsDNA level (IU/L) 29.42 (7.95–94.90) 9.49 (7.29–19.45)** 42.43 (13.38–98.88) 17.13 (7.77–31.99)**
C3 (g/L) 0.54 ± 0.26 0.88 ± 0.27** 0.46 ± 0.27 0.82 ± 0.34**
SLEDAI 16.2 ± 6.0 7.8 ± 4.0** 15.4 ± 6.5 7.1 ± 4.0**
  1. **Compared with the same parameters before treatment, P < 0.05