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The incidence of idiopathic inflammatory myopathies in the adult Slovenian population

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Abstract

Idiopathic Inflammatory myopathies (IIM) are rare disorders. The aim of our study was to determine the incidence of IIM in a well-defined Slovenian region. This retrospective study was conducted at the Department of Rheumatology, University Medical Centre Ljubljana, the only secondary/tertiary rheumatology center in a region with a population of 704,342 adults. We identified potential IIM cases by searching the electronic patient records for ICD-10 codes M33, M35.1, M35.8, M60, G72, G73, and J84. We included incipient IIM cases between January 2010 and December 2017, who were at the time of the diagnosis, residents of the inspected region. To avoid under-reporting due to miscoded cases, we obtained a list of the patients who had histological patterns consistent with IIM on muscle biopsy from the Institute of Pathology. The annual incidence rate for IIM was calculated. During the eight-year observation period, we identified 65 IIM cases (72.3% female, median (IQR) patient age 64.8 (54.8–73.2) years). The estimated annual incidence of IIM in the studied population was 11.5 (95% CI 9.0–14.6) per 106 adults, in females 16.2 (95% CI 12.1–21.4), and in males 6.6 (95% CI 4.0–10.2) per 106 adults. The incidence rate of IIM in Slovenia is consistent with data from the literature.

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Funding

The study was supported by the Slovenian Research Agency (ARRS) for the National Research Programme P3–0314.

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Authors and Affiliations

  1. Department of Rheumatology, University Medical Centre Ljubljana, Vodnikova cesta 62, 1000, Ljubljana, Slovenia

    Jaka Ostrovršnik, Alojzija Hočevar, Žiga Rotar, Monika Krošel, Saša Čučnik & Matija Tomšič

  2. Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia

    Alojzija Hočevar & Vesna Jurčić

  3. Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia

    Saša Čučnik

  4. Institute of Pathology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia

    Vesna Jurčić & Matija Tomšič

Authors
  1. Jaka Ostrovršnik
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  2. Alojzija Hočevar
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  3. Žiga Rotar
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  4. Monika Krošel
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  5. Saša Čučnik
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  6. Vesna Jurčić
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  7. Matija Tomšič
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Corresponding author

Correspondence to Jaka Ostrovršnik.

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The study was approved by the National Medical Ethics Committee.

Additional information

Rheumatology in Slovenia: Clinical practice and translational research

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Ostrovršnik, J., Hočevar, A., Rotar, Ž. et al. The incidence of idiopathic inflammatory myopathies in the adult Slovenian population. Clin Rheumatol 38, 279–283 (2019). https://doi.org/10.1007/s10067-018-4237-5

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  • DOI: https://doi.org/10.1007/s10067-018-4237-5

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