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Systemic sclerosis-rheumatoid arthritis overlap syndrome complicated with Sweet’s syndrome

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Abstract

Herein, we report a case of a 34-year-old woman with systemic sclerosis (SSc)-rheumatoid arthritis (RA) overlap syndrome (OS) complicated with Sweet’s syndrome. OS has been defined as entities satisfying classification criteria of at least two connective tissue diseases (CTD) occurring at the same or at different times in the same patient. The CTD include RA, SSc, systemic lupus erythematosus (SLE), polymyositis, and dermatomyositis. Sweet’s syndrome also known as acute febrile neutrophilic dermatosis was first described by Robert Sweet in 1964. Sweet’s syndrome is characterized by fever, neutrophilia, erythematous skin lesions, and a diffuse dermal infiltrate of mature neutrophils. There are sets of associations that we will discuss in this article between OS and Sweet’s syndrome.

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Fig. 1

Abbreviations

ACR :

American College of Rheumatology

CTD :

connective tissue diseases

ND :

neutrophilic dermatoses

OS :

overlap syndrome

RA :

rheumatoid arthritis

SLE :

systemic lupus erythematosus

SSc :

systemic sclerosis

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Funding

This study was supported by the National Natural Science Foundation of China (81371731). Milstein Medical Asian American Partnership Foundation (2017, Dermatology), and Education Reform Projects of Peking Union Medical College (No. 2016zlgc0106).

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Authors and Affiliations

  1. Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shuai Fu Yuan No.1, Dongcheng District, Beijing, 100730, China

    T. Zhu, W. L. Zhao, Y. P. Zeng, Y. H. Liu, H. Z. Jin & L. Li

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  1. T. Zhu
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  2. W. L. Zhao
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  3. Y. P. Zeng
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  4. Y. H. Liu
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  5. H. Z. Jin
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  6. L. Li
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Corresponding author

Correspondence to L. Li.

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Zhu, T., Zhao, W.L., Zeng, Y.P. et al. Systemic sclerosis-rheumatoid arthritis overlap syndrome complicated with Sweet’s syndrome. Clin Rheumatol 37, 2281–2284 (2018). https://doi.org/10.1007/s10067-018-4150-y

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  • DOI: https://doi.org/10.1007/s10067-018-4150-y

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