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Human microbiome, infections, and rheumatic disease

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Abstract

Microbes have coevolved with their human hosts for millions of years and are vital to their normal development and homoeostasis. It is now clear that there is direct and indirect cross talk between the microbiome and host immune responses. However, the exact mechanisms for this microbial influence in disease pathogenesis remain elusive and are now a major research focus.

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Funding

Supported by grant nos. K23AR064318 and R03AR072182 from NIAMS to Dr. Jose U Scher, the Colton Center for Autoimmunity, the Riley Family Foundation, and the Beatriz Snyder Foundation.

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Authors and Affiliations

  1. Sanatorio Parque, Universidad Nacional de Rosario, Rosario, Santa Fe, Argentina

    Ana Clara Caminer

  2. Psoriatic Arthritis Center, Division of Rheumatology, New York University Langone Health, New York, NY, USA

    Rebecca Haberman & Jose U. Scher

  3. Microbiome Center for Rheumatolgy and Autoimmunity (MiCRA), Division of Rheumatology, New York University School of Medicine and Hospital for Joint Diseases, New York, NY, USA

    Jose U. Scher

  4. Division of Rheumatology, NYU Hospital for Joint Diseases, Room 1608, 301 East 17th Street, New York, NY, 10003, USA

    Jose U. Scher

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  1. Ana Clara Caminer
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Correspondence to Jose U. Scher.

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Caminer, A.C., Haberman, R. & Scher, J.U. Human microbiome, infections, and rheumatic disease. Clin Rheumatol 36, 2645–2653 (2017). https://doi.org/10.1007/s10067-017-3875-3

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