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Clinical Rheumatology

, Volume 36, Issue 5, pp 1077–1082 | Cite as

Radiographic involvement of metacarpophalangeal and radiocarpal joints in hand osteoarthritis

  • Olga Addimanda
  • Carlotta Cavallari
  • Elettra Pignotti
  • Lia Pulsatelli
  • Luana Mancarella
  • Roberta Ramonda
  • Antonella Fioravanti
  • Riccardo Meliconi
Original Article

Abstract

To evaluate, by means of a longitudinal study, radiographic involvement of metacarpophalangeal and radio-carpal joints in hand osteoarthritis, its relationship with erosive disease and its progression, 368 patients with hand osteoarthritis were enrolled. All patients underwent hand X-rays. On the basis of the presence of central erosions in interphalangeal joints, patients were divided into three groups: 0—no central erosions, 1—one joint with central erosion, and 2—two or more joints with central erosions. A longitudinal study on 44 patients and nine normal controls, whose X-rays were available after 3.9 years, was performed. The radiological involvement of metacarpophalangeal and radio-carpal joints was evaluated using Kellgren-Lawrence and OARSI scores. Low number of joints showed Kellgren-Lawrence values ≥2 group 0, 42/1290 (3.3%); group 1, 10/410 (2.4%); and group 2, 36/1980 (1.8%). Low score values were obtained for all radiographic items. Only metacarpophalangeal joint space narrowing score showed significant increase from groups 0 to 2. Subsequent adjustment for age, gender, and BMI did not confirm the statistical significance. Marginal erosions were rarely found (6.7% of joints). Metacarpophalangeal and radio-carpal radiographic per patient scores significantly worsened at follow-up, but no significant increase in joints with Kellgren-Lawrence score ≥2 was found. In normal controls, no significant radiographic worsening was found. Only a minority of metacarpophalangeal joints shows a Kellgren-Lawrence value ≥2. Metacarpophalangeal and to lesser extent radiocarpal joints had significant worsening at follow-up. Metacarpophalangeal joint involvement in hand osteoarthritis is mild but progressive. Radiocarpal involvement is negligible.

Keywords

Imaging–radiology OA 

Notes

Acknowledgments

The authors thank Ms. Alexandra Teff for her linguistic assistance.

Compliance with ethical standards

Disclosures

None.

Funding

This study was partially supported by grants from Fondazione del Monte di Bologna e Ravenna, (Bologna), Rizzoli Orthopedic Institute/Italian Ministry of Health (Ricerca Corrente), and the University of Bologna (RFO). The study sponsor was not involved in the study design, collection, analysis and interpretation of data, in the writing of the manuscript, or in the decision to submit the manuscript for publication.

Supplementary material

10067_2017_3565_MOESM1_ESM.doc (74 kb)
ESM 1 (DOC 74 kb)
10067_2017_3565_MOESM2_ESM.doc (80 kb)
ESM 2 (DOC 80 kb)

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Copyright information

© International League of Associations for Rheumatology (ILAR) 2017

Authors and Affiliations

  1. 1.Medicine & Rheumatology UnitRizzoli Orthopaedic InstituteBolognaItaly
  2. 2.Dept of Biomedical & Neuromotor SciencesUniversity of BolognaBolognaItaly
  3. 3.Statistics UnitRizzoli Orthopaedic InstituteBolognaItaly
  4. 4.Immunorheumatology and Tissue regenerationRizzoli Orthopaedic InstituteBolognaItaly
  5. 5.DIMED, University of PadovaPadovaItaly
  6. 6.Rheumatology Unit, Department of Clinical Medicine and Immunological ScienceUniversity of SienaSienaItaly

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