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Acro-osteolysis is an osteolysis of the distal phalanges of the hands and feet and can affect the terminal tuft or the shaft of the distal phalanx (transverse or band acro-osteolysis). It is often associated with distal digital ischemia, digital calcinosis, or severe sensory neuropathy. Acro-osteolysis has been associated with a heterogeneous group of disorders, including occupational activities, infections, rheumatic disorders (systemic sclerosis, psoriatic arthritis), endocrinopathies, genetic disorders, and lysosomal storage disorders. Plain radiography is the gold standard for the detection of acro-osteolysis.

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Correspondence to Lazaros I. Sakkas.

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Botou, A., Bangeas, A., Alexiou, I. et al. Acro-osteolysis. Clin Rheumatol 36, 9–14 (2017).

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  • Digital ischemia
  • Infection
  • Psoriatic arthritis
  • Systemic sclerosis
  • Transverse acro-osteolysis