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Clinical Rheumatology

, Volume 34, Issue 10, pp 1737–1744 | Cite as

Effects of home-based exercise intervention on health-related quality of life for patients with ankylosing spondylitis: a meta-analysis

  • Hui Liang
  • Hua Zhang
  • Haiyan Ji
  • Chunmei Wang
Original Article

Abstract

The objective of this paper was to objectively evaluate the effectiveness of home-based exercise interventions for improving health-related quality of life in patients with ankylosing spondylitis (AS). Databases including PubMed, Web of Science, EMBASE, Ovid-Medline, and The Cochrane Library were electronically searched published from inception through October 2014 involving home-based exercise intervention in AS patients. Studies that measured the Bath Ankylosing Spondylitis Functional Index (BASFI), the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), depression and pain as outcomes were included. Studies involving patients with multiple diseases or received combinations of other interventions were excluded. Two independent investigators screened the identified articles, extracted the data, and assessed the methodological quality of the included studies. Qualitative descriptions were conducted, and quantitative analysis was performed with RevMan software (version 5.2). A total of six studies comprising 1098 participants were included in the study. Meta-analyses showed that home-based exercise interventions significantly reduced the BASFI scores (MD = −0.39, 95 % CI −0.57, −0.20, p = 0.001), BASDAI scores (MD = −0.50, 95 % CI −0.99, −0.02, p = 0.04), depression scores (MD = −2.31, 95 % CI −3.33, −1.30, p = 0.001), and for pain scores because of different evaluation methods among these studies; therefore, a subgroup analysis should be conducted for comparison. The results show that home-based exercise interventions can effectively improve the health-related quality of life in patients with AS. The benefit and clinical performance of home-based exercise care requires further investigation by a series of multicenter, large-sample size randomized controlled trails.

Keywords

Ankylosing spondylitis Home-based exercise intervention Meta-analysis Quality of life 

Notes

Disclosures

None.

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Copyright information

© International League of Associations for Rheumatology (ILAR) 2015

Authors and Affiliations

  1. 1.School of NursingTianjin Medical UniversityTianjinPeople’s Republic of China
  2. 2.Department of Rheumatology and Immunology, General HospitalTianjin Medical UniversityTianjinPeople’s Republic of China

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