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A meta-analysis of alcohol consumption and the risk of gout

Abstract

Alcohol consumption had been linked to the risk of gout theoretically, but the results from observational studies were conflicting. Hence, a meta-analysis was conducted to assess the effect of alcohol consumption on the risk of gout. A comprehensive search was performed to identify all eligible studies on the association of alcohol consumption with gout risk. Pooled relative risks (RRs) with 95 % confidence intervals (CIs) from fixed and random effects models were calculated. A total of 12 articles with 17 studies involving 42,924 cases met the inclusion criteria. The pooled RR for highest vs. non/occasional alcohol drinking in every study was 1.98 (95 % CI, 1.52–2.58). The RRs for light (≤1 drink/day), moderate (>1 to <3 drinks/day), and heavy drinking (≥3 drinks/day) vs. non/occasional alcohol drinking were 1.16 (95 % CI, 1.07–1.25), 1.58 (95 % CI, 1.50–1.66), and 2.64 (95 % CI, 2.26–3.09), respectively. The results suggested that alcohol consumption might be associated with increased risk of gout.

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Correspondence to Xiubo Jiang.

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Meiyun Wang and Xiubo Jiang equally contributed to this study.

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Wang, M., Jiang, X., Wu, W. et al. A meta-analysis of alcohol consumption and the risk of gout. Clin Rheumatol 32, 1641–1648 (2013). https://doi.org/10.1007/s10067-013-2319-y

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  • DOI: https://doi.org/10.1007/s10067-013-2319-y

Keywords

  • Alcohol consumption
  • Gout
  • Meta-analysis
  • Risk factor