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Knee vs hip single-joint intra-articular hyaluronic acid injection in patients with both hip and knee osteoarthritis: a pilot study

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Abstract

This paper aims to compare the results of single-joint knee vs hip hyaluronic acid (HA) injections in patients with osteoarthritis (OA) involving both the knee and hip joints. Thirty-eight patients who were diagnosed to have both hip and knee OA were enrolled. Patients were divided into two groups to receive HA injection three times at 1-week intervals either to the hip or knee joints. Pain level during activities and rest was measured by using visual analog scale (VAS). Western Ontario and McMaster University Osteoarthritis Index (WOMAC 5-point Likert 3.0) was also used prior to the injections and 1 month after the 3rd injection. In the knee injection group, the intragroup analysis revealed significant improvements in VAS activity pain, VAS rest pain, and WOMAC pain values following injection when compared with preinjection values, while no significant difference was detected in WOMAC stiffness, WOMAC physical function, and WOMAC total values. In the hip injection group, VAS activity pain, VAS rest pain, WOMAC pain, WOMAC stiffness, WOMAC physical function, and WOMAC total values showed significant improvement after the injection when compared with preinjection values. Although statistically not significant (p > 0.05), the comparison of the differences (preinjection–postinjection) between the groups demonstrated higher values in the hip injection group. We imply that intra-articular single-joint HA injections either to the knee or hip joints in OA patients with involvement of both of these joints are effective with regard to pain and functional status.

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Authors and Affiliations

  1. Department of Physical Medicine and Rehabilitation, Istanbul University Istanbul Medical Faculty, Istanbul, Turkey

    Demirhan Dıraçoğlu, Kerem Alptekin, Bahar Teksöz & Cihan Aksoy

  2. Department of Physical Medicine and Rehabilitation, Marmara University Medical School, Istanbul, Turkey

    İlker Yağcı

  3. Department of Physical Medicine and Rehabilitation, Gülhane Military Medical Academy Haydarpaşa Training Hospital, Istanbul, Turkey

    Levent Özçakar

  4. Department of Physical Medicine and Rehabilitation, Hacettepe University Medical School, Ankara, Turkey

    Levent Özçakar

  5. Istanbul Universitesi, Istanbul Tip Fakultesi, Fiziksel Tip ve Rehabilitasyon Anabilim Dali, 34093, Capa, Istanbul, Turkey

    Demirhan Dıraçoğlu

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  1. Demirhan Dıraçoğlu
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  2. Kerem Alptekin
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  3. Bahar Teksöz
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  4. İlker Yağcı
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  5. Levent Özçakar
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  6. Cihan Aksoy
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Correspondence to Demirhan Dıraçoğlu.

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Dıraçoğlu, D., Alptekin, K., Teksöz, B. et al. Knee vs hip single-joint intra-articular hyaluronic acid injection in patients with both hip and knee osteoarthritis: a pilot study. Clin Rheumatol 28, 1021–1024 (2009). https://doi.org/10.1007/s10067-009-1199-7

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  • DOI: https://doi.org/10.1007/s10067-009-1199-7

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