Abstract
Inclusion body myositis, although rare, is the commonest cause of myopathy in patients aged over 50 years. The suggested pathogenesis remains uncertain and its prognosis remains poor. There have been select case reports of its association with an inflammatory etiology and it is postulated that this group of patients respond better to immunosuppressive therapy. We therefore report a rare case of inclusion body myositis that responded well to immunosuppressive therapy. We also report the possibility of its association with infliximab therapy
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Dalakas MC (1991) Polymyositis, dermatomyositis and inclusion body myositis. N Engl J Med 325:1487–1498
Griggs RC, Askanas V, DiMauro S et al (1995) Inclusion body myositis and myopathies. Ann Neurol 38:705–713
Badsrising UA, Maat-Schieman M, van Duinen SG et al (2000) Epidemiology of inclusion body myositis in the Netherlands: a nationwide study. Neurology 55:1385–1388
Liu LWC, Tarnoposlky M, Armstrong D (2004) Injection of botulism toxin A to the upper esophageal sphincter for oropharyngeal dysphagia in two patients with inclusion body myositis. Can J Gastroenterol 18(6):397–399
Chahin N, Engel AG (2008) Correlation of muscle biopsy, clinical course, and outcome in PM and sIBM. Neurology 70(6):418–424
Engel WK, Askanas V (2006) Inclusion-body myositis: clinical, diagnostic, and pathologic aspects. Neurology 66:S20–S29
Derk CT, Vivino FB, Kenyon L, Mandel S (2003) Inclusion body myositis in connective tissue disorders: case report and review of the literature. Clin Rheumatol 22(4–5):324–328, Oct
Lotz BP, Engel AG, Nishino H, Stevens JC, Litchy WJ (1989) Inclusion body myositis. Observations in 40 patients. Brain 112:727–747
Musial J, Undas A, Celinska-Lowenhoff M (2003) Polymyositis associated with infliximab treatment for rheumatoid arthritis. Rheumatology (Oxford) 42(12):1566–1568, Dec
Vershuuren JJ, Badrising UA, Wintzen AR et al (1997) Inclusion body myositis: An underdiagnosed myopathy in older people. In: Emery AEH (ed) Diagnostic Criteria for Neuromuscular Disorders. European Neuromuscular Centre. 2nd edn. The Royal Society of Medicine, London, pp 81–84
Disclosures
None
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Kalla, R., Soumakiyan, M. & Tuck, S. A case of inclusion body myositis responsive to prednisolone therapy. Clin Rheumatol 28 (Suppl 1), 21–22 (2009). https://doi.org/10.1007/s10067-008-1047-1
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10067-008-1047-1