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Digital vasculitis: a late complication of anti-tumour necrosis factor alpha therapy

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Abstract

Anti-tumour necrosis factor alpha therapy has led to significant advancement in the treatment of rheumatological disease. Rarely, anti-TNFα antagonists have been associated with vasculitis, predominantly cutaneous leukocytoclastic vasculitis. We present the first case of angiographically-confirmed digital vasculitis occurring as a late complication of etanercept therapy. Our case adds to the limited repertoire of case reports of anti-TNFα induced vasculitis and highlights the potential risk of this serious complication occurring up to several years after initiation of these agents.

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Authors and Affiliations

  1. Rheumatology Department, Royal Adelaide Hospital, Eleanor Harrald Building, North Terrace, Adelaide, SA, 5000, Australia

    Pamela Mangat

  2. The Queen Elizabeth Hospital, Adelaide, Australia

    Samuel Whittle

  3. Royal Adelaide Hospital, Adelaide, Australia

    Les Cleland & Vidya Limaye

Authors
  1. Pamela Mangat
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  2. Samuel Whittle
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  3. Les Cleland
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  4. Vidya Limaye
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Correspondence to Pamela Mangat.

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Mangat, P., Whittle, S., Cleland, L. et al. Digital vasculitis: a late complication of anti-tumour necrosis factor alpha therapy. Clin Rheumatol 27, 1593–1595 (2008). https://doi.org/10.1007/s10067-008-1015-9

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  • DOI: https://doi.org/10.1007/s10067-008-1015-9

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