Skip to main content

Advertisement

Log in

A case of Takayasu arteritis complicated by Castleman’s disease

  • Case Report
  • Published:
Clinical Rheumatology Aims and scope Submit manuscript

Abstract

We describe the first case of Takayasu Arteritis (TA) complicated by multicentric hyaline-vascular type of Castleman’s disease (CD) which was diagnosed by the biopsy of mediastinal lymphnode 23 years after the diagnosis of TA. CD is classified as a lymphoid disorder of immune regulation characterized by a systemic, unregulated B cell proliferation, and there are some reports about the coincidence of CD and autoimmune diseases. This case has allowed us to gain some insight into a possible relation between the two disorders.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Ben-Chetrit E, Flusser D, Okon E et al (1989) Multicentric Castleman's disease associated with rheumatoid arthritis: a possible role of hepatitis B antigen. Ann Rheum Dis 48:326–330

    Article  PubMed  CAS  Google Scholar 

  2. Jacobs SA, Vidnovic N Patel H et al (2007) Durable remission of HIV-negative, Kaposi's sarcoma herpes virus-associated multicentric Castleman disease in patient with rheumatoid arthritis treated with methotrexate. Clin Rheumatol 26:1148–1150

    Article  PubMed  Google Scholar 

  3. Suwannaroj S, Elkins SL, McMurray RW (1999) Systemic lupus erythematosus and Castleman's disease. J Rheumatol 26:1400–1403

    PubMed  CAS  Google Scholar 

  4. Chorzelski T, Hashimoto T, Maciejewska B et al (1999) Paraneoplastic pemphigus associated with Castleman tumor, myasthenia gravis and bronchiolitis obliterans. J Am Acad Dermatol 41:393–400

    Article  PubMed  CAS  Google Scholar 

  5. Pacor ML, Peroli P, Givanni S et al (1990) Unicentric Castleman's lymphadenopathy presenting with Behçet's syndrome: a case report. Haematologica 75:470–472

    PubMed  CAS  Google Scholar 

  6. Lajoie G, Kumar S, Min KW et al (1995) Renal thrombotic microangiopathy associated with multicentric Castleman's disease. Report of two cases. Am J Surg Pathol 19:1021–1028

    Article  PubMed  CAS  Google Scholar 

  7. Couch WD (1980) Giant lymph node hyperplasia associated with thrombotic thrombocytopenic purpura. Am J Clin Pathol 74:340–344

    PubMed  CAS  Google Scholar 

  8. Nanki T, Tomiyama J, Arai S (1994) Mixed connective tissue disease associated with multicentric Castleman's disease. Scand J Rheumatol 23:215–217

    Article  PubMed  CAS  Google Scholar 

  9. Noris M, Daina E, Gamba S et al (1999) Interleukin-6 and RANTES in Takayasu arteritis: a guide for therapeutic decisions? Circulation 100(1):55–60

    PubMed  CAS  Google Scholar 

  10. Brandt SJ, Bodine DM, Dunbar CE et al (1990) Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice. J Clin Invest 86:592–599

    Article  PubMed  CAS  Google Scholar 

Download references

Disclosures

None

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Saeko Takahashi.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Takahashi, S., Kamiyama, I. & Ishizaka, A. A case of Takayasu arteritis complicated by Castleman’s disease. Clin Rheumatol 27 (Suppl 2), 71–73 (2008). https://doi.org/10.1007/s10067-008-1014-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10067-008-1014-x

Keywords

Navigation