Abstract
Osteonecrosis (ON) is a clinical entity characterized by death of bone marrow and trabecular bone as a result of disruption of blood supply to the bone. The antiphospholipid (APL) syndrome is characterized by arterial and/or venous thrombosis and pregnancy morbidity in association with APL antibodies. The involvement of multiple or atypical sites by ON has been reported, especially in association with APL antibodies. We described herein multiple and atypical infarcts which developed in a patient with primary APL syndrome.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Rosenthal E, Sangle SR, Khamashta MA, D’Cruz D, Hughes GR (2007) Orthopedic manifestations of the antiphospholipid syndrome. Rev Med Intern 28(2):103–107
Massando L, Jacobelli S, Leissner M, Gonzalez M, Villaroel L, Rivero S (1992) High dose intravenous methylprednisone therapy associated with osteonecrosis in patients with systemic lupus erythematosus. Lupus 2:401–405
Asherson RA, Liote F, Page B et al (1993) Avascular necrosis of bone and antiphospholipid antibodies in systemic lupus erythematosus. J Rheumatol 20:284–288
Yoo WH (2004) Multiple rib infarcts: a rare form of osteonecrosis in antiphospholipid syndrome. Ann Rheum Dis 63(4):457–458
Alijotas J, Argemi M, Barquinero J (1990) Kienbock’s disease and antiphospholipid antibodies. Clin Exp Rheumatol 8(3):297–298
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Rostom, S., Bahiri, R. & Hajjaj-Hassouni, N. Multifocal avascular necrosis revealing antiphospholipid syndrome. Clin Rheumatol 27, 271–272 (2008). https://doi.org/10.1007/s10067-007-0716-9
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10067-007-0716-9