Skip to main content

Advertisement

SpringerLink
Log in

Carnitine: a therapeutic option for childhood psoriatic onycho-pachydermo-periostitis (POPP)

  • Brief Report
  • Published:
Clinical Rheumatology Aims and scope Submit manuscript

Abstract

Psoriatic onycho-pachydermo-periostitis (POPP) is a rare subset of psoriatic arthritis, characterized by onychopathy, painful thickening of the periungual soft tissues, and radiological features consisting of an exuberant periosteal reaction of the terminal phalanx. The POPP treatment is debated, and side effect risk of therapies may not be offset by their benefits. We report on a successful treatment with carnitine in a 15-year old boy suffering from POPP.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Fietta P, Manganelli P (2005) Childhood onset of psoriatic onycho-pachydermo-periostitis (POPP). J Eur Acad Dermatol Venereol 19:780–782

    Article  PubMed  CAS  Google Scholar 

  2. Afeltra A, Amoroso A, Sgro P, Gandini L, Lenzi A (2004) Clinical improvement in psoriatic arthritis symptoms during treatment for infertility with carnitine. Clin Exp Rheumatol 22:138

    PubMed  CAS  Google Scholar 

  3. Fournié B, Viraben R, Durroux R, Lassoued S, Gay R, Fournié A (1989) Psoriatic onycho-pachydermo-periostitis of the big toe. Anatomo-clinical study and physiopathogenic approach apropos of 4 cases. Rev Rhum Mal Osteoartic 56:579–582

    PubMed  Google Scholar 

  4. Boisseau-Garsaud AM, Beylot-Barry M, Doutre MS, Beylot C, Baran R (1996) Psoriatic onycho-pachydermo-periostitis. A variant of psoriatic distal interphalangeal arthritis? Arch Dermatol 132:176–180

    Article  PubMed  CAS  Google Scholar 

  5. De Pontville M, Dompmartin A, De Raucourt S, Macro M, Remond B, Leroy D (1993) Psoriatic onycho-pachydermo-periostitis. Ann Dermatol Venereol 120:229–232

    PubMed  Google Scholar 

  6. Goupille P, Laulan J, Vedérè V, Kaplan G, Valat JP (1995) Psoriatic onycho-periostitis. Scand J Rheumatol 24:53–54

    PubMed  CAS  Google Scholar 

  7. Bauza A, Redondo P, Aquerreta D (2000) Psoriatic onycho-pachydermo-periostitis: treatment with methotrexate. Br J Dermatol 143:901–902

    Article  PubMed  CAS  Google Scholar 

  8. Jury CS, Fleming C, Kemmett D (2000) Severe nail dystrophy associated with painful fingertips. Diagnosis: psoriatic onychopachydermoperiostitis (POPP). Arch Dermatol 136:925–930

    Article  PubMed  CAS  Google Scholar 

  9. Dosik JS (2001) Psoriatic onycho-pachydermo-periostitis. Dermatol Online J 7:11

    PubMed  CAS  Google Scholar 

  10. Kroiss MM, Vogt T, Finkenzeller T, Landthaler M, Stolz W (2002) Psoriatic onycho-pachydermo-periostitis. Z Rheumatol 61:598–600

    Article  PubMed  CAS  Google Scholar 

  11. Anders HJ, Sanden S, Kruger K (2002) Psoriatic onycho-pachydermo-periostitis. Z Rheumatol 61:601–604

    Article  PubMed  CAS  Google Scholar 

  12. Bongartz T, Härle P, Friedrich S, Karrer S, Vogt T, Seitz A et al (2005) Successful treatment of psoriatic onycho-pachydermo periostitis (POPP) with adalimumab. Arthritis Rheum 52:280–282

    Article  PubMed  CAS  Google Scholar 

  13. Kiziltunc A, Cogalgil S, Cerrahoglu L (1998) Carnitine and antioxidant levels in patients with rheumatoid arthritis. Scand J Rheumatol 27:441–445

    Article  PubMed  CAS  Google Scholar 

  14. Azzini M, Girelli D, Olivieri O et al (1995) Fatty acids and anti-oxidant micronutrients in psoriatic arthritis. J Rheumatol 22:103–108

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Osteo-Articular Department, Rheumatic Disease and Internal Medicine Unit, Hospital and University of Parma, Via Gramsci, 14, 43100, Parma, Italy

    Pieranna Fietta & Paolo Manganelli

Authors
  1. Pieranna Fietta
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Paolo Manganelli
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Pieranna Fietta.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Fietta, P., Manganelli, P. Carnitine: a therapeutic option for childhood psoriatic onycho-pachydermo-periostitis (POPP). Clin Rheumatol 26, 93–94 (2007). https://doi.org/10.1007/s10067-006-0322-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10067-006-0322-2

Keywords

Search

Navigation