Abstract
With the broad employment of immunosuppressive therapy, the incidence of Pseudallescheria boydii infections is rising. We report a first case of the localized subcutaneous P. boydii infection in a patient with microscopic polyangiitis. Favorable outcome related to the treatment with voriconazole adds to the growing body of evidence supporting the use of this particular agent in P. boydii infections.
References
Tadros TS, Workowski KA, Siegel RJ, Hunter S, Schwartz DA (1998) Pathology of hyalohyphomycosis caused by Scedosporium apiospermum (Pseudallescheria boydii): an emerging mycosis. Hum Pathol 29:1266–1272
Idigoras P, Perez-Trallero E, Pineiro L, Larruskain J, Lopez-Lopategui MC, Rodriguez N, Gonzalez JM (2001) Disseminated infection and colonization by Scedosporium prolificans: a review of 18 cases, 1990–1999. Clin Infect Dis 32:E158–E165
Berenguer J, Rodriguez-Tudela JL, Richard C, Alvarez M, Sanz MA, Gaztelurrutia L, Ayats J, Martinez-Suarez JV (1997) Deep infections caused by Scedosporium prolificans. A report on 16 cases in Spain and a review of the literature. Scedosporium Prolificans Spanish Study Group. Medicine (Baltimore) 76:256–265
Cuenca-Estrella M, Ruiz-Diez B, Martinez-Suarez JV, Monzon A, Rodriguez-Tudela JL (1999) Comparative in-vitro activity of voriconazole (UK-109,496) and six other antifungal agents against clinical isolates of Scedosporium prolificans and Scedosporium apiospermum. J Antimicrob Chemother 43:149–151
Zeng J, Kamei K, Zheng Y, Nishimura K (2004) Susceptibility of Pseudallescheria boydii and Scedosporium apiospermum to new antifungal agents. Nippon Ishinkin Gakkai Zasshi 45:101–104
Munoz, P, Marin M, Torneo P, Martin Rabadan P, Rodriguez-Creixems M, Bouza E (2000) Successful outcome of Scedosporium apiospermum disseminated infection treated with voriconazole in a patient receiving corticosteroid therapy. Clin Infect Dis 31:1499–1501
Bosma F, Voss A, van Hamersvelt HW, de Sevaux RG, Biert J, Kullberg BJ, Melchers WG, Verweij PE (2003) Two cases of subcutaneous Scedosporium apiospermum infection treated with voriconazole. Clin Microbiol Infect 9:750–753
Fays S, Cesare MP, Antunes A, Truchetet F (2002) Cutaneous and osteoarticular Scedosporium apiospermum infection. Ann Med Interne (Paris) 153:537–539
Chaveiro MA, Vieira R, Cardoso J, Afonso A (2003) Cutaneous infection due to Scedosporium apiospermum in an immunosuppressed patients. J Eur Acad Dermatol Venereol 17:47–49
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Lainščak, M., Hočevar, A., Logar, D. et al. Subcutaneous infection with Pseudallescheria boydii in an immunocompromised patient. Clin Rheumatol 26, 1023–1024 (2007). https://doi.org/10.1007/s10067-006-0263-9
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DOI: https://doi.org/10.1007/s10067-006-0263-9