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Non-rheumatoid erosive arthritis associated with type I hereditary angioedema

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Abstract

Hereditary angioedema (HAE) is an autosomal dominant disease that causes recurrent attacks of non-pitting edema of soft tissues, without pruritus. This disorder can also affect internal organs. The cause of HAE consists in quantitative or qualitative defective production of C1 inhibitor (C1-INH). Many autoimmune diseases such as systemic lupus erythematosus (SLE) (or SLE-like syndromes), Sjögren’s syndrome, scleroderma, thyroiditis, glomerulonephritis, and inflammatory bowel disease have been described in patients suffering from HAE. A concomitance with pure arthritis was previously reported only in two adult patients. Here, we describe for the first time the association between HAE and a non-rheumatoid erosive oligoarthritis involving hips and wrists.

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Authors and Affiliations

  1. Division of Rheumatology, “Villa Pini” Clinic, Chieti, Italy

    C. Palazzi & E. Pennese

  2. First Division of Internal Medicine, “Spirito Santo” Hospital, Pescara, Italy

    E. D’Amico & P. Cacciatore

  3. Rheumatology Department of Lucania, “S. Carlo” Hospital, Potenza and “Madonna delle Grazie” Hospital, Matera, Italy

    I. Olivieri

  4. Via Legnago 23, 65123, Pescara, Italy

    C. Palazzi

Authors
  1. C. Palazzi
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  2. E. D’Amico
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  3. P. Cacciatore
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  4. E. Pennese
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  5. I. Olivieri
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Corresponding author

Correspondence to C. Palazzi.

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Palazzi, C., D’Amico, E., Cacciatore, P. et al. Non-rheumatoid erosive arthritis associated with type I hereditary angioedema. Clin Rheumatol 24, 632–633 (2005). https://doi.org/10.1007/s10067-005-1097-6

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  • DOI: https://doi.org/10.1007/s10067-005-1097-6

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