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Acute cholecystitis at initial presentation of polyarteritis nodosa

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Abstract

Polyarteritis nodosa (PAN) is a systemic vasculitis of unknown etiology. Although gastrointestinal involvement may be seen in half of the cases of PAN, vasculitis of the gallbladder at the disease onset is a rare presentation. We report a case of a 48-year-old man who was admitted due to acute cholecystitis. He had complained of myalgia, fever and weight loss for about one month prior to admission. At physical examination, mild hypertension and calf pain were noted. He underwent a cholecystectomy; histopathological evaluation disclosed necrotizing vasculitis suggestive of PAN. We emphasize that cholecystitis may be part of the initial presentation of systemic vasculitis.

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Acknowledgements

K. Metze was supported by “Research of CNPq”.

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Correspondence to Sandra Regina Muchinechi Fernandes.

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Fernandes, S.R.M., Samara, A.M., Magalhães, E.P. et al. Acute cholecystitis at initial presentation of polyarteritis nodosa. Clin Rheumatol 24, 625–627 (2005). https://doi.org/10.1007/s10067-005-1092-y

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  • DOI: https://doi.org/10.1007/s10067-005-1092-y

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