Abstract
The authors report a 40-year-old Caucasian man with relapsing muscle and skin involvement of dermatomyositis treated with high-dose corticosteroids, taken orally, and methotrexate and human gamma globulin, both administered intravenously. After 4 months of aggressive treatment, he presented with generalized edema, considered secondary to dermatomyositis. Aggressive immunosuppression did not stop disease progression. The literature concerning anasarca due to inflammatory myopathies is revised.
References
Medsger TA, Oddis CV (1998) Inflammatory muscle disease. In: Klippel JH, Dieppe PA (eds) Rheumatology. Mosby, London, pp 1–14
Venables GS et al (1982) Acute polymyositis with subcutaneous edema. J Neurol Sci 55:161–164
Gorelik O, Almoznino-Sarafian D, Alon I et al (2001) Acute inflammatory myopathy with severe subcutaneous edema, a new variant? Report of two cases and review of the literature. Rheumatol Int 20:163–166
Lyon-Caen O, Bouche P, Chaunu MP, Duyckaerts C, Vitoux JF (1985) Acute polymyositis with spontaneously regressive subcutaneous edema. Rev Neurol (Paris) 141:749–752
Nitsche A (2000) Edema de tronco y de pared abdominal en dermatomyositis. Medicina (B Aires) 48:331–332
Smyth AE, Bell AL (2000) Acute oedematous dermatomyositis. Ann Rheum Dis 59:574–575
Andonopoulos AP, Gogos CA, Tzanakakis G (1993) Subcutaneous edema: an “unrecognized” feature of acute polymyositis. Rheumatol Int 13:159–161
Mroue KH, Sharana NH, Rbeiz JG, Arayssi TK (2003) A case of edematous dermatomyositis. J Rheum 30:2722–2723
Mitchell JP, Dennis GJ, Rider LG (2001) Juvenile dermatomyositis with ansarca: a possible indicator of severe disease activity. J Pediatr 138:942–945
Mehndiratta S, Banerjee P (2004) Juvenile dermatomyositis presenting with anasarca. Indian Pediatr 41:752–753
Karabiber H, Aslan M, Alkan A, Yakinci C (2004) A rare complication of generalized edema in juvenile dermatomyositis: a report of one case. Brain Dev 26:269–272
Bohan A, Peter JB (1975) Polymyositis and dermatomyositis. N Engl J Med 292:403–407
Go RS, Call TG (2000) Deep venous thrombosis of the arm after intravenous immunoglobulin infusion: case report and literature review of intravenous-related thrombotic complications. Mayo Clin Proc 75(1):83–85
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Werner de Castro, G., Appenzeller, S., Bértolo, M. et al. Acute dermatomyositis with subcutaneous generalized edema. Clin Rheumatol 25, 898–900 (2006). https://doi.org/10.1007/s10067-005-0053-9
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DOI: https://doi.org/10.1007/s10067-005-0053-9