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Kawasaki disease in an infant following immunisation with hepatitis B vaccine


The known association between hepatitis B and vasculitis has been reported in rare cases in adults after hepatitis B vaccination. We here describe a 35-day-old infant who developed Kawasaki disease 1 day after receiving his second dose of hepatitis B vaccine. Although extremely rare, this possible side effect should be noted and further investigated.

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Fig. 1
Fig. 2





Left coronary artery


Right coronary artery


Polyarteritis nodosa


Kawasaki disease


Erythrocyte sedimentation rate


White blood cell


Left anterior descending


Left circumflex


Intravenous immunoglobulin


Computerized tomography


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Correspondence to Philip J. Hashkes.

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Miron, D., Fink, D. & Hashkes, P.J. Kawasaki disease in an infant following immunisation with hepatitis B vaccine. Clin Rheumatol 22, 461–463 (2003).

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  • Hepatitis B virus
  • Kawasaki disease
  • Vaccine