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A case of lithium toxicity with significant QT interval prolongation

Fallbericht: Lithium-Intoxikation mit erheblicher Verlängerung des QT-Intervalls

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Abstract

Background

Lithium toxicity has been associated with electrocardiographic abnormalities, such as QT interval prolongation.

Case report

An unresponsive patient with a history of alcohol abuse and recently diagnosed bipolar disorder was brought to the emergency department. An elevated lithium level of 4.7 mmol/L was found. The corrected QT interval was significantly prolonged at 727 ms. The patient was dialyzed and recovered fully.

Discussion

This case illustrates the importance of a systematic evaluation of all patients who may have been exposed to a toxic ingestion.

Zusammenfassung

Hintergrund

Lithiumvergiftungen können Veränderungen im EKG, wie eine Verlängerung des QT-Intervalls, hervorrufen.

Fallbericht

Eine Patientin mit Alkoholabhängigkeit und vor kurzem diagnostizierter bipolarer Störung wurde nicht ansprechbar eingeliefert. Eine erhöhte Lithium-Konzentration von 4,7 mmol/L wurde festgestellt. Es zeigte sich eine QTc-Verlängerung auf 727 ms. Die Patientin wurde dialysiert und erreichte eine vollständige Genesung.

Diskussion

Dieser Fall illustriert die Wichtigkeit einer systematischen Evaluierung aller Patienten, bei denen eine Vergiftung möglich erscheint.

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Authors and Affiliations

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Correspondence to T.K. Becker MD.

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Conflict of interest

The authors have no conflicts of interest. This submission did not receive any external financial support.

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Redaktion

Prof. Dr. M. Fischer, Göppingen

Prof. Dr. K.-G. Kanz, München

Prof. Dr. W. Schreiber, Wien

Prof. Dr. F. Walcher, Magdeburg

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Becker, T., Hariri, H. A case of lithium toxicity with significant QT interval prolongation. Notfall Rettungsmed 18, 227–230 (2015). https://doi.org/10.1007/s10049-015-0008-x

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  • DOI: https://doi.org/10.1007/s10049-015-0008-x

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