Skip to main content
SpringerLink
Log in

Präklinische Gabe von Prothrombinkomplex-Konzentrat PPSB bei Schädel-Hirn-Trauma unter oraler Antikoagulation

Prehospital administration of prothrombin complex concentrate PPSB for head injuries under oral anticoagulation

  • Notfall aktuell - Für Sie gelesen
  • Published:
Notfall + Rettungsmedizin Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Abb. 1

Literatur

  1. Bershad EM, Suarez JI (2010) Prothrombin complex concentrates for oral anticoagulant therapy-realted intracranial hemorrhage: a review of the literature. Neurocrit Care 12:403–413

    Article  PubMed  CAS  Google Scholar 

  2. Beynon C, Hertle DN, Unterberg AW, Sakowitz OW (2012) Clinical review: traumatic brain injury in patients receiving antiplatelet medication. Crit Care 16:228

    PubMed  Google Scholar 

  3. Bonville D, Ata A, Jahraus C et al (2011) Impact of preinjury warfarin and antiplatelet agents on outcome of trauma patients. Surgery 150:861–868

    Article  PubMed  Google Scholar 

  4. Bundesärztekammer (2008) Querschnitts-Leitlinien (BÄK) zur Therapie mit Blutungskomponenten und Plasmaderivaten, 4. Aufl. http://www.bundesaerztekammer.de/page.asp?his=0.6.3288. Zugegriffen: 06 Juni 2013

  5. Deutsche Gesellschaft für Unfallchirurgie (2012) TraumaRegister DGU®, http://www.traumaregister.de. Zugegriffen: 06. Juni 2013

  6. Dossett L, Riesel J, Griffin M et al (2011) Prevalence and implications of preinjury warfarin use: an analysis of the National Trauma Databank. Arch Surg 146:565–570

    Article  PubMed  Google Scholar 

  7. Günther SA, Stegmaier J, Paul AO et al (2011) Leichtes Schädel-Hirn-Trauma unter Antikoagulation. Notfall Rettungsmed 14:268–274

    Article  Google Scholar 

  8. Imberti D, Barillari G, Biasioli C et al (2008) Prothrombin complex concentrates for urgent anticoagulation reversal in patients with intracranial haemorrhage. Pathophysiol Haemost Thromb 36:259–265

    Article  PubMed  CAS  Google Scholar 

  9. Joseph B, Hadjizacharia P, Aziz H et al (2013) Prothrombin complex concentrate: an effective therapy in reversing the coagulopathy of traumatic brain injury. J Trauma Acute Care Surg 74:248–253

    Article  PubMed  CAS  Google Scholar 

  10. Kuwashiro T, Yasaka M, Itabashi R et al (2011) Effect of prothrombin complex concentrate on hematoma enlargement and clinical outcome in patients with anticoagulant-associated intracerebral hemorrhage. Cerebrovasc Dis 31:170–176

    Article  PubMed  CAS  Google Scholar 

  11. Lendrum RA, Kotze JP, Lockey DJ, Weaver AE (2013) Case studies in prehospital care from London HEMS: pre-hospital administration of prothrombin complex concentrate to the head-injured patient. Emerg Med J 30:247–248

    Article  PubMed  Google Scholar 

  12. Rendell S, Batchelor JS (2012) An analysis of predictive markers for intracranial haemorrhage in warfarinised head injury patients. Emerg Med J 30:28–31

    Article  PubMed  Google Scholar 

  13. Rossaint R, Bouillon B, Cerny V et al (2013) The STOP the Bleeding Campaign. Critical Care 17:136

    Article  PubMed  Google Scholar 

  14. Spahn DR, Bouillon B, Cerny V et al (2013) Management of bleeding and coagulopathy following major trauma: an updated European guideline. Crit Care 17:R76

    Article  PubMed  Google Scholar 

  15. Tauber M, Koller H, Moroder P et al (2009) Secondary intracranial hemorrhage after mild head injury in patients with low-dose acetylsalicylate acid prophylaxis. J Trauma 67:521–525

    Article  PubMed  CAS  Google Scholar 

Download references

Einhaltung der ethischen Richtlinien

Interessenkonflikt. L.E. Ocker und B.A. Leidel geben an, dass kein Interessenkonflikt besteht.

Author information

Authors and Affiliations

  1. Klinik für Allgemeine, Unfall-, Hand- und Plastische Chirurgie, Klinikum der Universität München, Nußbaumstraße 20, 80336, München, Deutschland

    L.E. Ocker

  2. Interdisziplinäre Rettungsstelle/Notfallaufnahme, Charité – Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Deutschland

    B.A. Leidel

  3. Luftrettungszentrum RTH Christoph 31 der ADAC-Luftrettung GmbH und Notarztstützpunkt NEF 4205 der Berliner Feuerwehr, Charité – Universitätsmedizin Berlin, Berlin, Deutschland

    B.A. Leidel

Authors
  1. L.E. Ocker
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. B.A. Leidel
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to L.E. Ocker.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ocker, L., Leidel, B. Präklinische Gabe von Prothrombinkomplex-Konzentrat PPSB bei Schädel-Hirn-Trauma unter oraler Antikoagulation. Notfall Rettungsmed 16, 556–558 (2013). https://doi.org/10.1007/s10049-013-1758-y

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10049-013-1758-y

Search

Navigation