Skip to main content
Log in

An association between a subset of Finnish late-onsetAlzheimer’s disease and alpha2-macroglobulin

  • Letter to the Editors
  • Published:
Neurogenetics Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Liao A, Nitsch RM, Greenberg SM, Finckh U, Blacker D, Albert M, Rebeck GW, Gomez-Isla T, Clatworthy A, Binetti G, Hock C, Mueller-Thomsen T, Mann U, Zuchowski K, Beisiegel U, Staehelin H, Growdon JH, Tanzi RE, Hyman BT (1998) Genetic association of an alpha2-macroglobulin (Val1000lle) polymorphism and Alzheimer’s disease. Hum Mol Genet 7:1953–1956

    Article  CAS  PubMed  Google Scholar 

  2. Myllykangas L, Polvikoski T, Sulkava R, Verkkoniemi A, Crook R, Tienari PJ, Pusa AK, Niinisto L, O’Brien P, Kontula K, Hardy J, Haltia M, Perez-Tur J (1999) Genetic association of alpha2-macroglobulin with Alzheimer’s disease in a Finnish elderly population. Ann Neurol 46:382–390

    Article  CAS  PubMed  Google Scholar 

  3. Gibson AM, Singleton AB, Smith G, Woodward R, McKeith IG, Perry RH, Ince PG, Ballard CG, Edwardson JA, Morris CM (2000) Lack of association of the alpha2-macroglobulin locus on chromosome 12 in AD. Neurology 54:433–438

    Article  CAS  PubMed  Google Scholar 

  4. Mirra SS, Heyman A, McKeel D, Sumi SM, Crain BJ, Brownlee LM, Vogel FS, Hughes JP, Belle G van, Berg L (1991) The Consortium to Establish a Registry for Alzheimer’s Disease (CERAD). II. Standardization of the neuropathologic assessment of Alzheimer’s disease. Neurology 41:479–486

    Article  CAS  PubMed  Google Scholar 

  5. Nagy Z, Esiri MM, Jobst KA, Johnston C, Litchfield S, Sim E, Smith AD (1995) Influence of the apolipoprotein E genotype on amyloid deposition and neurofibrillary tangle formation in Alzheimer’s disease. Neuroscience 69:757–761

    Article  CAS  PubMed  Google Scholar 

  6. Kuusisto J, Koivisto K, Mykkanen L, Helkala EL, Vanhanen M, Hanninen T, Kervinen K, Kesaniemi YA, Riekkinen PJ, Laakso M (1997) Association between features of the insulin resistance syndrome and Alzheimer’s disease independently of apolipoprotein E4 phenotype: cross sectional population based study. BMJ 315:1045–1049

    Article  CAS  PubMed Central  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to H. Soininen.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Pirskanen, M., Alafuzoff, I., Hiltunen, M. et al. An association between a subset of Finnish late-onsetAlzheimer’s disease and alpha2-macroglobulin. Neurogenetics 3, 171–172 (2001). https://doi.org/10.1007/s100480100110

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s100480100110

Keywords

Navigation