Skip to main content
SpringerLink
Log in

Further exclusion of FSHD1B from the telomeric region of 10q

  • SHORT COMMUNICATION
  • Published:
Neurogenetics Aims and scope Submit manuscript

ABSTRACT

The localization of the gene for the majority of cases of facioscapulohumeral muscular dystrophy is established as 4q35-qter (FSHD1A), although locus heterogeneity has been demonstrated with a minority of families unlinked to 4q. In FSHD1A, the disease is associated with a deletion of 3.3 kb repeats from a tandem repeat located near the as-yet-unidentified gene. This repeat cross-hybridizes with a telomeric region on 10q, making this cross-hybridizing region a feasible candidate gene for FSHD1B. We have tested the most telomeric marker on 10q (sAVA4) and excluded ∼17 cM on either side of this marker as harboring the FSHD1B gene.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Author information

Authors and Affiliations

  1. Duke University Medical Center, Department of Medicine, Section of Medical Genetics, Durham, NC 27710, USA, , , , , , US

    M.C. Speer, M.A. Pericak-Vance, J.M. Stajich, J. Sarrica & M. Jordan

  2. Duke University Medical Center, Department of Medicine, Division of Neurology, Durham, NC 27710, USA, , , , , , US

    A.D. Roses, J.M. Vance & J.R. Gilbert

Authors
  1. M.C. Speer
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M.A. Pericak-Vance
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. J.M. Stajich
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. J. Sarrica
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. M. Jordan
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. A.D. Roses
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. J.M. Vance
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. J.R. Gilbert
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Received June 5, 1997; Revised and Accepted July 14, 1997

Rights and permissions

Reprints and permissions

About this article

Cite this article

Speer, M., Pericak-Vance, M., Stajich, J. et al. Further exclusion of FSHD1B from the telomeric region of 10q. Neurogenetics 1, 151–152 (1997). https://doi.org/10.1007/s100480050023

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s100480050023

Search

Navigation