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Polygenic variants related to familial hypobetalipoproteinemia in a patient with Alzheimer’s disease homozygotic for the APOE ε2 allele presenting multiple cortical superficial siderosis and recurrent lobar hemorrhages

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The data that support the findings of this study are available from the corresponding author upon reasonable request.

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Funding

This work was supported by the KAKENHI program of the Japan Society for the Promotion of Science (Grant Numbers: JP18K07491 (M. I.), JP19K07411 (H. Y.), JP19H03712 (S. I.), and JP19K07813 (Y. I.)) from the Ministry of Education, Culture, Sports, Science and Technology of Japan.

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Correspondence to Masaki Ikeda.

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This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committee of Geriatrics Research Institute and Hospital (No. 52) and the Human Genome/Gene Analysis Research Ethics Committee of Gunma University (No. 62).

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Ikeda, M., Okamoto, K., Suzuki, K. et al. Polygenic variants related to familial hypobetalipoproteinemia in a patient with Alzheimer’s disease homozygotic for the APOE ε2 allele presenting multiple cortical superficial siderosis and recurrent lobar hemorrhages. Neurogenetics (2021). https://doi.org/10.1007/s10048-021-00672-3

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