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Flow analysis during mock circulation in normal and aortic arch aneurysm models through an aortic cannula toward the aortic arch and root

Journal of Artificial Organs volume 24, pages 442–449 (2021)Cite this article

Abstract

The aim of this study was to elucidate flow patterns of two different types of aortic cannulas inserted from the ascending aorta toward the aortic arch and root by mock circulation in a normal aortic arch and an aortic arch aneurysm model. Extracorporeal circulation was established using a centrifugal pump, a transparent glass normal aortic arch model, and an aortic arch aneurysm model for measurement by particle image velocimetry. The Stealthflow and Dispersion cannulas were used to elucidate the characteristics of the flow pattern and velocity under the condition of the cannula tip toward the aortic arch and aortic root. In the normal aortic arch model, high-velocity exit flow ranging from 0.7 to 0.8 m/s was detected in the proximal aortic arch by directing the cannula tip toward the aortic arch, whereas flow velocity in the aortic arch was < 0.2 m/s by directing the cannula tip toward the aortic root. In the aortic arch aneurysm model, high-velocity exit flow ranging from 0.5 to 0.8 m/s was detected in the aortic arch by directing the cannula tip toward the aortic arch, whereas flow velocity in the aortic arch was decreased to less than 0.2 m/s by directing the cannula tip toward the aortic root. Directing the aortic cannula tip toward the aortic root allowed the high-velocity exit flow to attenuate in velocity, so that flow velocity in the aortic arch was sufficiently reduced by reversed flow and vortex formation in both the normal and aortic arch aneurysm models.

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Acknowledgements

This study was supported by JSPS KAKENHI Grant Number 24592044.

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Affiliations

  1. Department of Clinical Engineering, Hirosaki University School of Medicine and Hospital, 53 Hon-cho, Hirosaki, Aomori, 036-8563, Japan

    Takeshi Goto

  2. Department of Thoracic and Cardiovascular Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori, 036-8562, Japan

    Ikuo Fukuda & Masahito Minakawa

  3. Graduate School of Science and Technology, Hirosaki University, Hirosaki, Aomori, Japan

    Takao Inamura & Minori Shirota

Authors
  1. Takeshi Goto
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  2. Ikuo Fukuda
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  3. Takao Inamura
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  4. Minori Shirota
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  5. Masahito Minakawa
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Contributions

All authors have made substantial contributions to all of the following: TG, IF, and MM conception and design of the study. TG acquisition of data. TI and MS analysis and interpretation of data. TG, MM, and IF drafting the article or revising it critically for important intellectual content. Final approval of the version to be submitted.

Corresponding authors

Correspondence to Takeshi Goto or Masahito Minakawa.

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Conflict of interest

Dr. Ikuo Fukuda is an inventor of the Stealthflow cannula. All other authors declare that they have no conflict of interest.

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Goto, T., Fukuda, I., Inamura, T. et al. Flow analysis during mock circulation in normal and aortic arch aneurysm models through an aortic cannula toward the aortic arch and root. J Artif Organs 24, 442–449 (2021). https://doi.org/10.1007/s10047-021-01267-3

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  • DOI: https://doi.org/10.1007/s10047-021-01267-3

Keywords

  • Aortic cannula
  • Cardiopulmonary bypass
  • Aortic root direction
  • Stealthflow cannula
  • Dispersion cannula