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A preliminary investigation of symptom pattern and prevalence before and up to 6 months after implantation of a left ventricular assist device

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Abstract

Despite increased use of left ventricular assist devices (LVAD) in patients with advanced or end-stage heart failure; little is known about the reoccurrence of common heart failure symptoms (e.g., fatigue) after LVAD implantation. The objective of this study was to investigate the prevalence and pattern of selected heart failure symptoms and identify changes in symptom patterns before and up to 6 months after LVAD implantation. We used self-report questionnaires to collect data from patients (n = 12) and measure symptoms at baseline, 1 and 2 weeks, and 1, 3, and 6 months after LVAD. We found that high levels of fatigue, anxiety, depression, and sleep disturbance were prevalent during these periods. However, we did not find any significant changes in symptom pattern over time. The preliminary findings set the starting point for large-scale studies fundamental to advances in symptom-management research in LVAD and for other patients living with artificial organs.

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References

  1. Dew MA, Kormos RL, Winowich S, Nastala CJ, Borovetz HS, Roth LH, Sanchez J, Griffith BP. Quality of life outcomes in left ventricular assist system inpatients and outpatients. ASAIO J. 1999;45:218–25.

    Article  PubMed  CAS  Google Scholar 

  2. Rose EA, Gelijns AC, Moskowitz AJ, Heitjan DF, Stevenson LW, Dembitsky W, Long JW, Ascheim DD, Tierney AR, Levitan RG, Watson JT, Meier P, Ronan NS, Shapiro PA, Lazar RM, Miller LW, Gupta L, Frazier OH, Desvigne-Nickens P, Oz MC, Poirier VL. Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med. 2001;345:1435–43.

    Article  PubMed  CAS  Google Scholar 

  3. Grady KL, Meyer PM, Mattea A, Dressler D, Ormaza S, White-Williams C, Chillcott S, Kaan A, Loo A, Todd B, Klemme A, Piccione W, Costanzo MR. Change in quality of life from before to after discharge following left ventricular assist device implantation. J Heart Lung Transpl. 2003;22:322–33.

    Article  Google Scholar 

  4. Grady KL, Meyer PM, Dressler D, Mattea A, Chillcott S, Loo A, White-Williams C, Todd B, Ormaza S, Kaan A, Costanzo MR, Piccione W. Longitudinal change in quality of life and impact on survival after left ventricular assist device implantation. Ann Thorac Surg. 2004;77:1321–7.

    Article  PubMed  Google Scholar 

  5. Allen JG, Weiss ES, Schaffer JM, Patel ND, Ullrich SL, Russell SD, Shah AS, Conte JV. Quality of life and functional status in patients surviving 12 months after left ventricular assist device implantation. J Heart Lung Transpl. 2010;29:278–85.

    Article  Google Scholar 

  6. Coyle LA, Ising MS, Gallagher C, Bhat G, Kurien S, Sobieski MA, Slaughter MS. Destination therapy: one-year outcomes in patients with a body mass index greater than 30. Artif Organs. 2010;34:93–7.

    Article  PubMed  Google Scholar 

  7. Rogers JG, Aaronson KD, Boyle AJ, Russell SD, Milano CA, Pagani FD, Edwards BS, Park S, John R, Conte JV, Farrar DJ, Slaughter MS. Continuous flow left ventricular assist device improves functional capacity and quality of life of advanced heart failure patients. J Am Coll Cardiol. 2010;55:1826–34.

    Article  PubMed  Google Scholar 

  8. Nordgren L, Sorensen S. Symptoms experienced in the last six months of life in patients with end-stage heart failure. Eur J Cardiovasc Nurs. 2003;2:213–7.

    Article  PubMed  Google Scholar 

  9. Broström A, Strömberg A, Dahlström U, Fridlund B. Sleep difficulties, daytime sleepiness, and health-related quality of life in patients with chronic heart failure. J Cardiovasc Nurs. 2004;19:234–42.

    PubMed  Google Scholar 

  10. Redeker NS. Sleep disturbance in people with heart failure: implications for self-care. J Cardiovasc Nurs. 2008;23:231–8.

    PubMed  Google Scholar 

  11. Krupp LB, LaRocca NG, Muir-Nash J, Steinberg AD. The fatigue severity scale. Application to patients with multiple sclerosis and systemic lupus erythematosus. Arch Neurol. 1989;46:1121–3.

    Article  PubMed  CAS  Google Scholar 

  12. Grieve FG, Harris DS, Fairbanks SD. Extending the Fatigue Severity Scale to an obese population. Eat Weight Disord. 2000;5:161–5.

    PubMed  CAS  Google Scholar 

  13. Buguet A, Cespuglio R, Radomski MW. Sleep and stress in man: an approach through exercise and exposure to extreme environments. Can J Physiol Pharmacol. 1998;76:553–61.

    Article  PubMed  CAS  Google Scholar 

  14. Williams VSL, Morlock RJ, Feltner D. Psychometric evaluation of a visual analog scale for the assessment of anxiety. Health Qual Life Outcomes. 2010;8:57. http://www.hqlo.com/content/pdf/1477-7525-8-57.pdf. Accessed 11 April 2011.

  15. Beck AT. BDI-II Beck depression inventory manual. San Antonio: Harcourt Assessment; 1996.

    Google Scholar 

  16. Evangelista LS, Dracup K, Moser DK, Westlake C, Erickson V, Hamilton MA, Fonarow GC. Two-year follow-up of quality of life in patients referred for heart transplant. Heart Lung. 2005;34:187–93.

    Article  PubMed  Google Scholar 

  17. Smith M. The psychometric properties of two sleep quality scales. J Undergrad Res. 2002;3(12) (Online). http://www.clas.ufl.edu/jur/200208/papers/paper_smith.html. Accessed 14 April 2011.

  18. Slaughter MS, Pagani FD, Rogers JG, Miller LW, Sun B, Russell SD, Starling RC, Chen L, Boyle AJ, Chillcott S, Adamson RM, Blood MS, Camacho MT, Idrissi KA, Petty M, Sobieski M, Wright S, Myers TJ, Farrar DJ. Clinical management of continuous-flow left ventricular assist devices in advanced heart failure. J Heart Lung Transpl. 2010;29:S1–39.

    Article  Google Scholar 

  19. Goldstein NE, Lynn J. Trajectory of end-stage heart failure. Perspect Biol Med. 2006;49:10–8.

    Article  PubMed  Google Scholar 

  20. Jurgens CY, Moser DK, Armola R, Carlson B, Sethares K, Riegel B. Symptom clusters of heart failure. Res Nurs Health. 2009;32:551–60.

    Article  PubMed  Google Scholar 

  21. Lee KS, Song EK, Lennie TA, Frazier SK, Chung ML, Heo S, Wu JR, Rayens MK, Riegel B, Moser DK. Symptom clusters in men and women with heart failure and their impact on cardiac event-free survival. J Cardiovasc Nurs. 2010;25:263–72.

    PubMed  Google Scholar 

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Acknowledgment

Funds were received from Wayne State University Research Grant.

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Correspondence to Jesus M. Casida or Jessica Parker.

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Casida, J.M., Parker, J. A preliminary investigation of symptom pattern and prevalence before and up to 6 months after implantation of a left ventricular assist device. J Artif Organs 15, 211–214 (2012). https://doi.org/10.1007/s10047-011-0622-4

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  • DOI: https://doi.org/10.1007/s10047-011-0622-4

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