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Bileaflet mechanical heart valve closing sounds: in vitro classification by phonocardiographic analysis

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Abstract

Bileaflet mechanical heart valves, which exhibit hemodynamic performance fairly similar to that of native valves, can be investigated by the analysis of their closing sounds. Signal spectra calculated from the closing sounds are characterized by specific features that are suitable for the functional evaluation of the valves. Five commercial bileaflet mechanical heart valves were studied under different conditions that were simulated in vitro using a Sheffield pulse duplicator for the aortic position. The closing sounds were acquired by means of a phonocardiographic apparatus, analyzed by a specifically implemented algorithm, and were statistically compared. This article was aimed at classifying the investigated valves on the basis of their signal spectra: different profiles were identified, depending on the working conditions; moreover, closing sound reproducibility and intensity allowed the ranking of valve performances with respect to the “noise” produced by valve closure. In particular, results demonstrated which valves were characterized by the lowest noise (i.e., the Medtronic Advantage and St. Jude Regent valves) and which were characterized by the highest reproducibility (OnX, Medtronic Advantage, and St. Jude Regent valves) under the examined experimental conditions.

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References

  1. Fallon AM, Marzec UM, Hansonb SR, Yoganathanc AP. Thrombin formation in vitro in response to shear-induced activation of platelets. Thromb Res 2007;121:397–406

    Article  PubMed  CAS  Google Scholar 

  2. Blome-Eberwein SA, Mrowinski D, Hofmeister J, Hetzer R. Impact of mechanical heart valve prosthesis sound on patients’ quality of life. Ann Thorac Surg 1 1996;61(2):594–602

    Article  CAS  Google Scholar 

  3. Donnerstein RL. An in vivo analysis of ultrasonic signals created by closing bileaflet mechanical heart valves. In: Engineering in Medicine and Biology Society, 1996. Bridging disciplines for biomedicine. Proceedings of the 18th Annual International Conference of the IEEE, vol 3. Washington, DC: IEEE, 1996;1343–1344

    Google Scholar 

  4. Bagno A, Anzil F, Tarzia V, Pengo V, Ruggeri A, Gerosa G. Application of wavelet analysis to the phonocardiographic signal of mechanical heart valve closing sounds. Int J Artif Organs 2009;32:166–172

    PubMed  Google Scholar 

  5. Sugiki H, Shiiya N, Murashita T, Yasuda K. Bileaflet mechanical valve sound analysis using a continuous wavelet transform. J Artif Organs 2006;9:42–49

    Article  PubMed  Google Scholar 

  6. Sugiki H, Shiiya N, Murashita T, Kunihara T, Matsuzaki K, Kubota T, Matsui Y, Sugiki K. Wavelet analysis of bileaflet mechanical valve sounds. J Artif Organs 2007;10(1):16–21

    Article  PubMed  Google Scholar 

  7. Sugiki H, Murashita T, Shiiya N, Matsui Y, Sugiki K. Wavelet analysis of valve closing sound detects malfunction of bileaflet mechanical valve. J Artif Organs 2008;11(1):29–37

    Article  PubMed  Google Scholar 

  8. Bagno A, Anzil F, Buselli R, Tarzia V, Pengo V, Gerosa G. Is the analysis over the time domain or over the frequency domain significant for the detection of bileaflet mechanical heart valve dysfunction? Ann Thorac Surg 2009;87:986–987

    Article  PubMed  Google Scholar 

  9. Bottio T, Caprili L, Casarotto D, Gerosa G. Small aortic annulus: the hydrodynamic performances of five commercially available bileaflet mechanical valves. J Thorac Cardiovasc Surg 2004;128:457–462

    Article  PubMed  Google Scholar 

  10. Bagno A, Buselli R, Anzil F, Tarzia V, Pengo V, Ruggeri A, Bottio T, Gerosa G. In vitro characterization of bileaflet mechanical heart valves closing sound. 35th Annual Computers in Cardiology Conference, September 14–17, 2008, Bologna, Italy

  11. Razzolini R, Gerosa G, Leoni L, Casarotto D, Chioin R, Dalla Volta S. Transaortic gradient is pressure-dependent in a pulsatile model of the circulation. J Heart Valve Dis 1999;8:279–283

    PubMed  CAS  Google Scholar 

  12. Sheffield Pulse Duplicator Instruction Manual, The University of Sheffield, Department of Medical Physics and Clinical Engineering, Royal Hallamshire Hospital, Sheffield, UK

  13. King MJ, Corden J, David T, Fisher J. A three-dimensional, timedependent analysis of flow through a bileaflet mechanical heart valve: comparison of experimental and numerical results. J Biomech 1996;29(5):609–618

    Article  PubMed  CAS  Google Scholar 

  14. King MJ, David T, Fisher J. Three-dimensional study of the effect of two leaflet opening angles on the time-dependent flow through a bileaflet mechanical heart valve. Med Eng Phys 1997;19:235–241

    Article  PubMed  CAS  Google Scholar 

  15. Fritzsche D, Eitz T, Laczkovics A, Liebold A, Knaut M, Matschke K, Sagie A, Mehlhorn U, Horstkotte D, Koerfer R. Early detection of mechanical valve dysfunction using a new home monitoring device. Ann Thorac Surg 2007;83:542–548

    Article  PubMed  Google Scholar 

  16. Welch PD. The use of fast Fourier transform for the estimation of power spectra: a method based on time averaging over short, modified periodograms. IEEE Trans Audio Electroacoust 1967;AU-15:70–73

    Article  Google Scholar 

  17. Nuttall AH. Some windows with very good sidelobe behavior. IEEE Trans Acoust Speech Signal Process 1981;29:84–91

    Article  Google Scholar 

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Correspondence to Andrea Bagno.

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Bagno, A., Anzil, F., Buselli, R. et al. Bileaflet mechanical heart valve closing sounds: in vitro classification by phonocardiographic analysis. J Artif Organs 12, 172–181 (2009). https://doi.org/10.1007/s10047-009-0470-7

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  • DOI: https://doi.org/10.1007/s10047-009-0470-7

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