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Journal of Artificial Organs

, Volume 12, Issue 3, pp 200–205 | Cite as

Maxillofacial reconstruction using custom-made artificial bones fabricated by inkjet printing technology

  • Hideto Saijo
  • Kazuyo Igawa
  • Yuki Kanno
  • Yoshiyuki Mori
  • Kayoko Kondo
  • Koutaro Shimizu
  • Shigeki Suzuki
  • Daichi Chikazu
  • Mitsuki Iino
  • Masahiro Anzai
  • Nobuo Sasaki
  • Ung-il Chung
  • Tsuyoshi Takato
Original Article

Abstract

Ideally, artificial bones should be dimensionally compatible with deformities, and be biodegradable and osteoconductive; however, there are no artificial bones developed to date that satisfy these requirements. We fabricated novel custom-made artificial bones from α-tricalcium phosphate powder using an inkjet printer and implanted them in ten patients with maxillofacial deformities. The artificial bones had dimensional compatibility in all the patients. The operation time was reduced due to minimal need for size adjustment and fixing manipulation. The postsurgical computed tomography analysis detected partial union between the artificial bones and host bone tissues. There were no serious adverse reactions. These findings provide support for further clinical studies of the inkjet-printed custom-made artificial bones.

Key words

Artificial bones Custom made α-Tricalcium phosphate (TCP) Inkjet printing Maxillofacial reconstruction 

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Copyright information

© The Japanese Society for Artificial Organs 2009

Authors and Affiliations

  • Hideto Saijo
    • 1
  • Kazuyo Igawa
    • 1
  • Yuki Kanno
    • 1
  • Yoshiyuki Mori
    • 1
  • Kayoko Kondo
    • 1
  • Koutaro Shimizu
    • 3
  • Shigeki Suzuki
    • 3
  • Daichi Chikazu
    • 1
  • Mitsuki Iino
    • 1
  • Masahiro Anzai
    • 4
  • Nobuo Sasaki
    • 5
  • Ung-il Chung
    • 2
  • Tsuyoshi Takato
    • 1
  1. 1.Department of Oral and Maxillofacial Surgery, Faculty of MedicineUniversity of TokyoTokyoJapan
  2. 2.Division of Tissue EngineeringUniversity of Tokyo HospitalTokyoJapan
  3. 3.Biomechanics Development CenterTokyoJapan
  4. 4.Advanced Development and Supporting CenterRIKENSaitamaJapan
  5. 5.Laboratory of Veterinary Surgery, Faculty of AgricultureUniversity of TokyoTokyoJapan

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