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Determination of the scattering coefficient of biological tissue considering the wavelength and absorption dependence of the anisotropy factor

  • Special Section: Regular Paper
  • The 5th Asian and Pacific-Rim Symposium on Biophotonics, (APBP’15), Yokohama, Japan
  • Published:
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Abstract

The anisotropy factor g, one of the optical properties of biological tissues, has a strong influence on the calculation of the scattering coefficient μ s in inverse Monte Carlo (iMC) simulations. It has been reported that g has the wavelength and absorption dependence; however, few attempts have been made to calculate μ s using g values by taking the wavelength and absorption dependence into account. In this study, the angular distributions of scattered light for biological tissue phantoms containing hemoglobin as a light absorber were measured by a goniometric optical setup at strongly (405 nm) and weakly (664 nm) absorbing wavelengths to obtain g. Subsequently, the optical properties were calculated with the measured values of g by integrating sphere measurements and an iMC simulation, and compared with the results obtained with a conventional g value of 0.9. The μ s values with measured g were overestimated at the strongly absorbing wavelength, but underestimated at the weakly absorbing wavelength if 0.9 was used in the iMC simulation.

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Authors and Affiliations

  1. Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka, 565-0871, Japan

    Daichi Fukutomi, Katsunori Ishii & Kunio Awazu

  2. Graduate School of Frontier Biosciences, Osaka University, 1-3 Yamadaoka, Suita, Osaka, 565-0871, Japan

    Kunio Awazu

  3. Global Center for Medical Engineering and informatics, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan

    Kunio Awazu

Authors
  1. Daichi Fukutomi
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  2. Katsunori Ishii
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  3. Kunio Awazu
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Correspondence to Kunio Awazu.

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Fukutomi, D., Ishii, K. & Awazu, K. Determination of the scattering coefficient of biological tissue considering the wavelength and absorption dependence of the anisotropy factor. Opt Rev 23, 291–298 (2016). https://doi.org/10.1007/s10043-015-0161-y

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  • DOI: https://doi.org/10.1007/s10043-015-0161-y

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