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Transillumination Laser Computed Tomography System with Fiber-Optic-Based Coherent Detection Imaging Method - High Spatial-Resolution and Quantitative Tomographic Imaging of Highly Scattering Objects -

  • ENVIRONMENTAL, BIOLOGICAL, AND SPACE OPTICS
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Abstract

We recently proposed and developed a novel transillumination laser computed tomography (CT) imaging system using a fiber-optic method based on coherent detection imaging (CDI) for biomedical use. Use of optical fibers enables portability and robustness against environmental changes in a room, such as variable temperature, air-flow shifts, and unexpected vibrations. In addition, motion-artifact-free images can be obtained because measurements can be performed with the object fixed. In the present paper, we experimentally investigate in detail the fundamental imaging properties of the system, which has a spatial resolution of 500 μm, a dynamic range of approximately 120 dB, and a minimum-detectable-optical power of 10−14W as a result of the excellent properties of the heterodyne detection. Based on experimental observations, the proposed system can reconstruct tomographic images of highly scattering objects in the transillumination mode, similar to X-ray CT, at sub-millimeter spatial resolution and with quantitativeness. Finally, we demonstrate with experiments using a physical phantom that the imaging system possesses high resolution and quantitative imaging abilities for highly scattering objects.

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Authors and Affiliations

  1. Faculty of Engineering, Yamagata University, 4-3-16 Jonan, Yonezawa, Yamagata, 992-8510, Japan

    Yoshiaki Sasaki, Jota Suzuki, Hiroki Inage, Ryota Emori, Shinji Tanosaki, Tetsuya Yuasa & Takao Akatsuka

  2. I.T. Research, Co., Ltd., 21st Century Plaza, 2-1-4 Takamori, Izumi-ku, Sendai, Miyagi, 981-3203, Japan

    Shinji Tanosaki

  3. School of Medicine, Yamagata University, 2-2-2 Iida-Nishi, Yamagata, Yamagata, 990-0031, Japan

    Michiaki Takagi & Akira Ishikawa

  4. Faculty of Engineering, Iwate University, 4-3-5 Ueda, Morioka, Iwate, 020-8551, Japan

    Hiroshi Taniguchi

  5. New Focus, Inc., 5215 Hellyer Avenue, San Jose, CA, 95138-1001, USA

    Balasigamani Devaraj

Authors
  1. Yoshiaki Sasaki
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  2. Jota Suzuki
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  3. Hiroki Inage
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  4. Ryota Emori
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  5. Shinji Tanosaki
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  6. Tetsuya Yuasa
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  7. Michiaki Takagi
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  8. Akira Ishikawa
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  9. Hiroshi Taniguchi
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  10. Balasigamani Devaraj
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  11. Takao Akatsuka
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Sasaki, Y., Suzuki, J., Inage, H. et al. Transillumination Laser Computed Tomography System with Fiber-Optic-Based Coherent Detection Imaging Method - High Spatial-Resolution and Quantitative Tomographic Imaging of Highly Scattering Objects -. OPT REV 10, 462–465 (2003). https://doi.org/10.1007/s10043-003-0462-4

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  • DOI: https://doi.org/10.1007/s10043-003-0462-4

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