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Gelenkknorpel, Arthrose und zelluläre Reparatur

Joint cartilage, osteoarthritis and cell-based repair

  • Leitthema
  • Published:
Trauma und Berufskrankheit

Zusammenfassung

Die Biochemie und Zellbiologie des Knorpelgewebes werden mit Blick auf Arthrose, Knorpelregeneration und -reparatur betrachtet. Dieser Beitrag gibt einen Überblick über den Knorpelzellstoffwechsel und will dazu beitragen, die aktuellen Bemühungen in der Etablierung von zellbasierten Behandlungsmöglichkeiten bei Knorpelschäden nach Trauma oder bei frühen Stadien arthrotischer Degeneration besser verstehen zu können.

Abstract

The biochemistry and cell biology of cartilage are presented with reference to osteoarthritis and cartilage regeneration and repair. This review aims at an integrative view of cartilage and chondrocyte metabolism to facilitate the interpretation of current efforts to devise cell-based orthopaedic treatment options for use in cartilage trauma and the early stages of osteoarthritic degeneration.

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Authors and Affiliations

  1. NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen, Markwiesenstraße 55, 72770, Reutlingen, Deutschland

    K. Benz &  J. Mollenhauer

  2. TETEC AG, Reutlingen, Deutschland

    J. Mollenhauer

  3. Medizinische Fakultät, Universität Jena, Jena, Deutschland

    J. Mollenhauer

  4. Department of Biochemistry, Rush University Medical Center, Chicago, IL, USA

    J. Mollenhauer

Authors
  1. K. Benz
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  2. J. Mollenhauer
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Correspondence to J. Mollenhauer.

Additional information

Diese Arbeit wurde in Teilen vom Bundesministerium für Bildung und Forschung (BMBF) gefördert (FKZ 0313400, 0313141, 0313755).

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Benz, K., Mollenhauer, J. Gelenkknorpel, Arthrose und zelluläre Reparatur. Trauma Berufskrankh 9, 235–241 (2007). https://doi.org/10.1007/s10039-007-1270-z

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  • DOI: https://doi.org/10.1007/s10039-007-1270-z

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