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Testicular Mixed Germ Cell Tumor With Polyembryoma Component in Brothers


We report the case of a 17-year-old male with a testicular tumor and high serum levels of α-fetoprotein. The patient was treated with surgery followed by combination chemotherapy with bleomycin, etoposide, and cisplatin. Histologic examination showed features of a mixed germ cell tumor composed of mature teratoma, immature teratoma, embryonal carcinoma, yolk sac tumor, and polyembryoma. He is currently well, and his serum levels of α-fetoprotein have been normal more than 5 months after treatment. His brother, aged 17 years at the time, had a similar tumor removed from the right testicle 5 years previously.

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Correspondence to Sevgi Bakarı ıs.

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Bakarı ıs, S., Resı ım, S. & Tunalı ı, N. Testicular Mixed Germ Cell Tumor With Polyembryoma Component in Brothers. Pediatr Dev Pathol 8, 92–97 (2005).

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  • testicular cancer
  • mixed germ cell neoplasm
  • testicle
  • polyembryoma
  • histology