Skip to main content
Log in

Nasal Chondromesenchymal Hamartoma: Report of a Case and Review of the Literature

  • Case report
  • Published:
Pediatric and Developmental Pathology


The sinonasal region is the site of several hamartomatous lesions, the majority of which are mesenchymal, with vascular hamartomas predominating. The occurrence of hamartomas in the nasal cavity of infants and children is especially rare. Nasal chondromesenchymal hamartoma (NCMH) is a rare lesion of the intranasal sinuses generally diagnosed in the newborn period, with the eldest reported patient presenting at 16 years of age. This neoplasm is composed of mesenchymal-stromal and chondroid tissue in varying proportions. It is felt to be analogous to the mesenchymal hamartoma of the chest wall, a lesion of similar histology generally involving the ribs and chest wall of neonates. To the best of our knowledge, only 14 cases of NCMH have been reported to date. We report a case of NCMH in an 11-year-old boy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1.
Figure 2.
Figure 3.
Figure 4.

Similar content being viewed by others


  1. MB McDermott TB Ponder LP Dehner (1998) ArticleTitleNasal chondromesenchymal hamartoma: an upper respiratory analogue of the chest wall mesenchymal hamartoma Am J Surg Pathol 22 425–433 Occurrence Handle1:STN:280:DyaK1c7ps1yitQ%3D%3D Occurrence Handle10.1097/00000478-199804000-00006 Occurrence Handle9537469

    Article  CAS  PubMed  Google Scholar 

  2. C Hsueh S Hsueh F Gonzalez-Crussi T Lee J Su (2001) ArticleTitleNasal chondromesenchymal hamartoma in children: report of 2 cases with review of the literature Arch Pathol Lab Med 125 400–403 Occurrence Handle1:STN:280:DC%2BD3M7pvV2rug%3D%3D Occurrence Handle11231491

    CAS  PubMed  Google Scholar 

  3. M Alrawi M McDermott D Orr J Russell (2003) ArticleTitleNasal chondromesenchymal hamartoma presenting in an adolescent Int J Pediatr Otorhinolaryngol 67 669–672 Occurrence Handle1:STN:280:DC%2BD3s3isVajuw%3D%3D Occurrence Handle10.1016/S0165-5876(03)00067-3 Occurrence Handle12745162

    Article  CAS  PubMed  Google Scholar 

  4. RG Wang SC Jiang R Gu (1994) ArticleTitleThe cartilaginous nasal capsule and embryonic development of human paranasal sinuses J Otolaryngol 23 239–243 Occurrence Handle1:STN:280:DyaK2M%2FovFWjsQ%3D%3D Occurrence Handle7996621

    CAS  PubMed  Google Scholar 

  5. CF Adair LDR Thompson BM Wenig DK Heffner (1996) ArticleTitleChondroosseous and respiratory epithelial hamartomas of the sinonasal tract and nasopharynx (Abstract) Mod Pathol 9 100

    Google Scholar 

  6. RA McLeod DC Dahlin (1979) ArticleTitleHamartoma (mesenchymoma) of the chest wall in infancy Radiology 131 657–661 Occurrence Handle1:STN:280:DyaE1M7otV2mug%3D%3D Occurrence Handle10.1148/131.3.657 Occurrence Handle441372

    Article  CAS  PubMed  Google Scholar 

  7. NJ Roland MM Khine R Clarke D Van Velzen (1992) ArticleTitleA rare congenital intranasal polyp: mesenchymal chondrosarcoma of the nasal region J Laryngol Otol 106 1081–1083 Occurrence Handle1:STN:280:DyaK3s7jvFKmtA%3D%3D Occurrence Handle10.1017/S0022215100121814 Occurrence Handle1487666

    Article  CAS  PubMed  Google Scholar 

  8. BZ Pilch (2001) Head and Neck Surgical Pathology Lippincott Williams & Wilkins Philadelphia

    Google Scholar 

Download references

Author information

Authors and Affiliations


Corresponding author

Correspondence to Simon Bergman.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Norman, E., Bergman, S. & Trupiano, J. Nasal Chondromesenchymal Hamartoma: Report of a Case and Review of the Literature. Pediatr Dev Pathol 7, 517–520 (2004).

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: