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Splenopancreatic Field Abnormality Is Not Unique to Trisomy 13

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Pediatric and Developmental Pathology

Abstract

Splenopancreatic fusion is an uncommon finding, usually only seen as part of the splenopancreatic field abnormality associated with trisomy 13. It may present itself either as ectopic splenic tissue in the cauda pancreatis, as ectopic pancreatic tissue in the spleen or accessory spleen, or as fusion of the cauda pancreatis and splenic hilum. In this study, we report four unrelated congenital anomaly cases presenting trisomy 21, osteocraniostenosis syndrome, isolated congenital heart defect, and oligohydramnios sequence due to prune belly syndrome, in which fusion was observed. This demonstrates that, although it may be more common in trisomy 13, this phenomenon should not be interpreted as pathognomonic to that syndrome.

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Acknowledgments

The authors thank Deise Lucia Chesca Simões for her technical assistance. We are also grateful to FAEPA (Fundação de Apoio ao Ensino, Pesquisa e Assistência) for their financial support.

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Authors and Affiliations

  1. Department of Pathology, Ribeirão Preto Medical School, University of São Paulo, Av. Bandeirantes, 3900, Ribeirão Preto, SP, 14049-900, Brazil

    Luiz Cesar Peres, Gustavo Henrique T. de Sales Barbosa, Renata Scarpat Careta & Cristiane Miziara Nassif

  2. Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, 14049-900, Brazil

    João Monteiro de Pina-Neto, Liane R. Giuliani, Ciro Dresch Martinhago & Israel Gomy

Authors
  1. Luiz Cesar Peres
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  2. Gustavo Henrique T. de Sales Barbosa
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  3. Renata Scarpat Careta
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  4. Cristiane Miziara Nassif
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  5. João Monteiro de Pina-Neto
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  6. Liane R. Giuliani
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  7. Ciro Dresch Martinhago
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  8. Israel Gomy
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Correspondence to Luiz Cesar Peres.

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Peres, L., Barbosa, G., Careta, R. et al. Splenopancreatic Field Abnormality Is Not Unique to Trisomy 13. Pediatr. Dev. Pathol. 7, 91–94 (2004). https://doi.org/10.1007/s10024-003-6067-x

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  • DOI: https://doi.org/10.1007/s10024-003-6067-x

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