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Endodermal Sinus Tumor of the Parotid Gland in a Child

  • Case Report
  • Published:
Pediatric and Developmental Pathology

Abstract

We report a case of a 16-month-old girl with a primary endodermal sinus tumor (EST) of the parotid gland. The girl was admitted to the hospital with a left side cervical tumor with a quick growth (within 3 wk). The tumor was surgically resected. The gross examination showed a 7.0-cm hemorrhagic and fragmentized mass. Diagnosis of an EST was established on the hematoxylin and eosin-stained slides from the resected material. Elevated serum alpha-fetoprotein (AFP) levels were detected and follow-up examinations of the patient did not show ESTs in other locations or other manifestations due to the tumor. The patient received chemotherapy after the surgery and remained alive without evidence of disease at the time of this writing (2 years after the diagnosis). As far as we know, this is the second report in the literature of a parotid gland’s EST.

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Acknowledgments

The authors thank Jacques Sredni for the English review, and Fernando Augusto Soares for the suggestions given.

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Authors and Affiliations

  1. Department of Pathology, Hospital do Cäncer, Rua Professor Antonio Prudente 211, São Paulo 01509-900, Brazil

    Simone Treiger Sredni, Isabela Werneck da Cunha & Clóvis Antonio Lopes Pinto

  2. Laboratory of Cancer Genetics, Ludwig Institute for Cancer Research, Rua Professor Antonio Prudente 109, 4th Floor, São Paulo 01509-010, Brazil

    Simone Treiger Sredni & Luis Fernando Lopes

  3. Department of Head and Neck Surgery, Hospital do Câncer, Rua Professor Antonio Prudente 211, São Paulo 01509-900, Brazil

    José Magrin

  4. Department of Pediatrics, Hospital do Cãncer, Rua Professor Antonio Prudente 211, São Paulo 01509-900, Brazil

    Nevigolino Pereira de Carvalho Filho & Luis Fernando Lopes

Authors
  1. Simone Treiger Sredni
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  2. Isabela Werneck da Cunha
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  3. Nevigolino Pereira de Carvalho Filho
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  4. José Magrin
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  5. Clóvis Antonio Lopes Pinto
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  6. Luis Fernando Lopes
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Correspondence to Simone Treiger Sredni.

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Sredni, S., Cunha, I., de Carvalho Filho, N. et al. Endodermal Sinus Tumor of the Parotid Gland in a Child. Pediatr. Dev. Pathol. 7, 77–80 (2004). https://doi.org/10.1007/s10024-003-4048-8

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  • DOI: https://doi.org/10.1007/s10024-003-4048-8

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