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Inflammation and Cytokine Signaling in Aneurysms

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Annals of Vascular Surgery

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References

  1. Glagov S. Morphology of collagen and elastin fibers in atherosclerotic lesions. Adv Exp Med Biol 1975;82:767–773.

    Google Scholar 

  2. Sumner DS, Hokansen DE, Strandness DE. Stress-strain characteristics and collagen-elastin content of abdominal aortic aneurysms. Surg Gynecol Obstet 1970;130:459–466.

    CAS  PubMed  Google Scholar 

  3. Campa JS, Greenhalgh RM, Powell JT. Elastin degradation in abdominal aortic aneurysms. Atherosclerosis 1987;65:13–21.

    Article  CAS  PubMed  Google Scholar 

  4. Busuttil RW, Abou-Zamzam AM, Machleder HI. Collagenase activity of the human aorta: A comparison of patients with and without aortic aneurysms. Arch Surg 1980;115: 1373–1378.

    Article  CAS  PubMed  Google Scholar 

  5. Vine N, Powell JT. Metalloproteinases in degenerative aortic disease. Clinical Science 1991;81:233–239.

    CAS  PubMed  Google Scholar 

  6. Newman KM, Ogata Y, Malon AM, et al. Identification of matrix metalloproteinases 3 (stromelysin-1) and 9 (gelatinase B) in abdominal aortic aneurysm. Arterioscler Thromb 1994;14:1315–1320.

    Article  CAS  PubMed  Google Scholar 

  7. Irizarry E, Newman KM, Gandhi RH, et al. Demonstration of Interstitial Collagenase in Abdominal Aortic Aneurysm Disease. J Surg Res 1993;54:571–574.

    Article  CAS  PubMed  Google Scholar 

  8. Tilson MD, Elefriades J, Brophy CM. Tensile strength and collagen in abdominal aortic aneurysm disease. In: Greenhalgh RM, Mannick JA, Powell JT, eds. The Cause and Management of Aneurysms. London: WB Saunders, 1990; pp 97–104.

    Google Scholar 

  9. Koch AE, Haines GK, Rizzo RJ, et al. Human abdominal aortic aneurysms: Immunophentypic analysis suggesting an immune-mediated response. Am J Pathol 1990;137:1199–1213.

    CAS  PubMed Central  PubMed  Google Scholar 

  10. Yanagi H, Sasagur Y, Sugama K, et al. Production of tissue collagenase (matrix metalloproteinase 1) by human aortic smooth muscle cells in response to platelet-derived growth factor. Atherosclerosis 1992;91:207–216.

    Article  Google Scholar 

  11. Faggioli GL, Gargiulo M, Bertoni F, et al. Parietal inflammatory infiltrate in peripheral aneurysms of atherosclerotic origin. J Cardiovasc Surg 1992;33:331–336.

    CAS  Google Scholar 

  12. Okada Y, Katsuda S, Okada Y, et al. An elastolytic enzyme detected in the culture medium of human arterial smooth muscle cells. Cell Biol Int 1993;17(9)863–869.

    Article  Google Scholar 

  13. Pearce WH, Sweis I, Yao JST, et al. Interleukin-1β and tumor necrosis factor-α release in normal and diseased human infrarenal aortas. J Vasc Surg 1992;16:784–789.

    Article  CAS  PubMed  Google Scholar 

  14. Evans CH, Georgescu HI, Lin CW, et al. Inducible synthesis of collagenase and other neutral metalloproteinases by cells of aortic origin. J Surg Res 1991;51:339–404.

    Article  Google Scholar 

  15. Lee E, Vaughan DE, Parikh SH, et al. Regulation of matrix metalloproteinases and plasminogen activator inhibitor-1 synthesis by plasminogen in cultured human vascular smooth muscle cells. Circ Res 1996;78:44–49.

    Article  CAS  PubMed  Google Scholar 

  16. Newman KM, Malon AM, Shin RD, et al. Matrix metalloproteinases in abdominal aortic aneurysm: Characterization, purification, and their possible sources. Connect Tissue Res 1994;30:265–276.

    Article  CAS  PubMed  Google Scholar 

  17. Emonard H, Grimaud JA. Matrix metalloproteinases. A Review. Cell Mol Biol 1990;36(2):131–153.

    Google Scholar 

  18. Busuttil RW, Abou-ZamZam AM, Machleder HI. Collagenase activity of the human aorta: A comparison of patients with and without abdominal aortic aneurysms. Arch Surg 1980;115:1373–1378.

    Article  CAS  PubMed  Google Scholar 

  19. Webster MW, McAuley E, Steed DL, et al. Collagen stability and collagenolytic activity in the normal and aneurysmal human abdominal aorta. Am J Surg 1991;161:635–638.

    Article  CAS  PubMed  Google Scholar 

  20. Herron GS, Unemori E, Wong M, et al. Connective tissue proteinases and inhibitors in abdominal aortic aneurysms. Arterioscler Thromb 1991;11:1667–1677.

    Article  CAS  PubMed  Google Scholar 

  21. Tilson MD, Newman KM. Proteolytic mechanisms in the pathogenesis of aortic aneurysms. In: Yao JST, Pearce WH, eds. Aneurysms: New Findings and Treatments. Norwalk, CT: Appleton & Lange, 1994, pp. 3–10.

  22. McMillan WD, Patterson BK, Keen RR, et al. In situ localization and quantification of mRNA for 92kD Type IV collagenase and its inhibitor in aneurysmal, occlusive, and normal aorta. Thomb Vasc Biol 1995;15:1139–1144.

    Article  CAS  Google Scholar 

  23. Freestone T, Turner RJ, Coady A, et al. Inflammation and matrix metalloproteinases in the enlarging abdominal aortic aneurysm. Arterioscler Thromb Vasc Biol 1995;15:1145–1151.

    Article  CAS  PubMed  Google Scholar 

  24. McMillan WD, Patterson BK, Keen RR, et al. In situ localization and quantification of seventy-two kilodalton type IV collagenase in aneurysmal, occlusive, and normal aorta. J Vasc Surg 1995;22:295–305.

    Article  CAS  PubMed  Google Scholar 

  25. Ramshaw AL, Roskell DE, Parums DV. Cytokine gene expression in aortic adventitial inflammation associated with advanced atherosclerosis (chronic periaortitis). J Clin Pathol 1994;47:721–727.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  26. Koch AE, Haines GK, RJ, et al. Human abdominal aortic aneurysms: Immunophenotypic analysis suggesting an immune mediated response. Am J Pathol 1990;137:1199–1213.

    CAS  PubMed Central  PubMed  Google Scholar 

  27. Pasquinelli G, Gargiulo PM, Vici M, et al. An immunohistochemical study of inflammatory abdominal aortic aneurysms. J Submicrosc Cytol Pathol 1993;25(1):103–112.

    Google Scholar 

  28. Pearce WH, Koch AE. Cellular components and features of immune response in abdominal aortic aneurysms. Ann NY Acad Sci 1996;800:175–185.

    Article  CAS  PubMed  Google Scholar 

  29. Szekanecz, Shah, Harlow, et al. Interleukin-8 and tumor necrosis factor-alpha are involved in human aortic endothelial cell migration. Pathobiology 1994;62:134–139.

    Article  CAS  PubMed  Google Scholar 

  30. Szekanecz Z, Shah MR, Pearce WH, et al. Human atheroscleroticabdominal aortic aneurysms produce interleukin (IL)-6 and interferon-gamma but not IL-2 and IL-4: The possible role for IL-6 and interferon-gamma in vascular inflammation. Agents Actions 1994;41:1–4.

    Article  Google Scholar 

  31. Keen RR, Nolan KD, Cippolone M, et al. IL-1β induces differential gene expression in aortic smooth muscle cells. J Vasc Surg 1994;20:774–786.

    Article  CAS  PubMed  Google Scholar 

  32. Clinton SK, Libby P. Cytokines and growth factors in atherogenesis. Arch Path Lab Med 1992;116:1292–1300.

    CAS  PubMed  Google Scholar 

  33. White JV, Haas K, Phillips S, et al. Adventitial elastolysis is a primary event in aneurysm formation. J Vasc Surg 1993;17: 371–381.

    Article  CAS  PubMed  Google Scholar 

  34. Stehbens WE, Martin BJ. Ultrastructural alterations of collagen fibrils in blood vessel walls. Connect Tissue Res 1993; 29:319–331.

    Article  CAS  PubMed  Google Scholar 

  35. Dobrin PB, Baker WH, Gley WC. Elastolytic and collagenolytic studies of arteries. Arch Surg 1984;119:405–409.

    Article  CAS  PubMed  Google Scholar 

  36. Newman JC, Li, Schuler. Cellular localization of MMPs in the abdominal aortic aneurysm wall. J Vasc Surg 1994; 20(5):814–820.

    Article  Google Scholar 

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Authors and Affiliations

  1. Chicago, Illinois, France

    William D. McMillan MD & William H. Pearce MD

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  1. William D. McMillan MD
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  2. William H. Pearce MD
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McMillan, W., Pearce, W. Inflammation and Cytokine Signaling in Aneurysms. Annals of Vascular Surgery 11, 540–545 (1997). https://doi.org/10.1007/s100169900088

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  • DOI: https://doi.org/10.1007/s100169900088

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