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Atypical teratoid rhabdoid tumor located in the pineal region following prophylactic irradiation for acute lymphoblastic leukemia

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Abstract

Atypical teratoid rhabdoid tumor (AT/RT) is a rare entity. In the central nervous system, AT/RT generally arises from the posterior fossa of infants and behaves aggressively. AT/RT is reported to arise from the infratentorial region (63%) and other sites, such as the suprasellar region, cerebellopontine angle, and spinal cord. The pineal region is rare (6%) as a site of origin. Radiation-induced brain tumors are well known. In this report, we present a case of a pineal region tumor causing acute hydrocephalus that could be pathologically diagnosed as AT/RT following prophylactic cranial irradiation for acute lymphoblastic leukemia.

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Acknowledgment

We kindly thank Dr. Youichi Nakazato (Gunma University) for his excellent comments regarding the pathological diagnosis.

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Authors and Affiliations

  1. Department of Neurosurgery, Yamagata University Faculty of Medicine, 2-2-2 Iidanishi, Yamagata, 990-9585, Japan

    Atsushi Kuge, Shinya Sato, Kaori Sakurada, Sunao Takemura & Takamasa Kayama

  2. National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo, Japan

    Takamasa Kayama

Authors
  1. Atsushi Kuge
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  2. Shinya Sato
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  3. Kaori Sakurada
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  4. Sunao Takemura
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  5. Takamasa Kayama
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Correspondence to Atsushi Kuge.

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Kuge, A., Sato, S., Sakurada, K. et al. Atypical teratoid rhabdoid tumor located in the pineal region following prophylactic irradiation for acute lymphoblastic leukemia. Brain Tumor Pathol 29, 177–181 (2012). https://doi.org/10.1007/s10014-011-0075-8

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  • DOI: https://doi.org/10.1007/s10014-011-0075-8

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