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A nonspecific form of dysembryoplastic neuroepithelial tumor presenting with intractable epilepsy

Brain Tumor Pathology volume 22, pages 35–40 (2005)Cite this article

Abstract

We report here an intractable epilepsy case with fairly typical clinicoradiological features of dysembryoplastic neuroepithelial tumor (DNT), which means onset of seizures at a young age accompanying a medial temporal cystic lesion enclosed in cortical dysplasia (CD). The medial cystic lesion was composed of two morphologically distinct components; one was oligo-like and the other showed some tendency toward neuronal and glial differentiation, even though they were morphologically different from a so-called specific glioneural element (SGE). Epileptiform discharges were detected not only on the medial lesion but also on the lateral inferior temporal gyrus, which was confirmed as CD. According to both histopathological and clinical features, we named the lesion a nonspecific form of DNT.

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Affiliations

  1. Department of Neurosurgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan

    Namiko Nishida, Nobuhiro Mikuni, Rei Enatsu, Naoki Hayashi, Jun A Takahashi & Yasuaki Nakashima

  2. School of Health Sciences, Kyoto University, Kyoto, Japan

    Yoneko Hayase & Shigeru Amano

  3. Department of Histopathology, Kyoto University Graduate School of Medicine, Kyoto, Japan

    Nobuo Hashimoto

  4. Department of Neurology, Kyoto University Graduate School of Medicine, Kyoto, Japan

    Akio Ikeda

Authors
  1. Namiko Nishida
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  2. Yoneko Hayase
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  3. Nobuhiro Mikuni
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  4. Rei Enatsu
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  5. Naoki Hayashi
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  6. Jun A Takahashi
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  7. Yasuaki Nakashima
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  8. Akio Ikeda
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  9. Shigeru Amano
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  10. Nobuo Hashimoto
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Corresponding author

Correspondence to Nobuhiro Mikuni.

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Nishida, N., Hayase, Y., Mikuni, N. et al. A nonspecific form of dysembryoplastic neuroepithelial tumor presenting with intractable epilepsy. Brain Tumor Pathol 22, 35–40 (2005). https://doi.org/10.1007/s10014-005-0176-3

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  • DOI: https://doi.org/10.1007/s10014-005-0176-3

Keywords

  • Public Health
  • Cystic Lesion
  • Distinct Component
  • Intractable Epilepsy
  • Cortical Dysplasia