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Enzyme-free impedimetric glucose sensor based on gold nanoparticles/polyaniline composite film

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Abstract

A non-enzymatic impedimetric glucose sensor was fabricated based on the adsorption of gold nanoparticles (GNPs) onto conductive polyaniline (PANI)-modified glassy carbon electrode (GCE). The modified electrode (GCE/PANI/GNPs) was characterized by using cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and scanning electron microscopy (SEM). The determination of glucose concentration was based on the measurement of EIS with the mediation of electron transfer by ferricyanide ([Fe(CN)6]3−). The [Fe(CN)6]3− is reduced to ferrocyanide ([Fe(CN)6]4−), which in turn is oxidized at GCE/PANI/GNPs. An increase in the glucose concentration results in an increase in the diffusion current density of the [Fe(CN)6]4− oxidation, which corresponds to a decrease in the faradaic charge transfer resistance (R ct). A wide linear concentration range from 0.3 to 10 mM with a lower detection limit of 0.1 mM for glucose was obtained. The proposed sensor shows high sensitivity, good reproducibility, and stability. In addition, the sensor exhibits no interference from common interfering substances such as ascorbic acid, acetaminophen, and uric acid.

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Acknowledgments

This work was supported by The World Academy of Sciences (TWAS) Research Grant Program (Ref. 12–183 RG/CHE/AS_I and UNESCO FR 12–183 RG/CHE/AS_I). We thank Dr. Subrata Sarker at Hongik University for valuable discussion regarding electrochemical impedance spectroscopy.

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Authors and Affiliations

  1. Department of Chemistry, Jagannath University, Dhaka, 1100, Bangladesh

    A. J. Saleh Ahammad, Abdullah Al Mamun, Tania Akter, M. A. Mamun, S. Faraezi & F. Z. Monira

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  1. A. J. Saleh Ahammad
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  2. Abdullah Al Mamun
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  3. Tania Akter
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  4. M. A. Mamun
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  5. S. Faraezi
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  6. F. Z. Monira
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Correspondence to A. J. Saleh Ahammad.

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Ahammad, A.J.S., Al Mamun, A., Akter, T. et al. Enzyme-free impedimetric glucose sensor based on gold nanoparticles/polyaniline composite film. J Solid State Electrochem 20, 1933–1939 (2016). https://doi.org/10.1007/s10008-016-3199-2

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  • DOI: https://doi.org/10.1007/s10008-016-3199-2

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