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Electrochemical detection of propofol at the preanodized carbon electrode

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Abstract

Preanodized screen printed carbon electrode (SPCE) has been utilized for the detection of propofol. Here the preanodized SPCE possess the specific functional groups which help the detection and determination of propofol. The proposed SPCE shows a clear oxidation peak for the detection of propofol in pH 7.0 phosphate buffer solutions. Interestingly, it shows a well-defined individual oxidation peak for the detection of propofol in the presence interferences (mixture of ascorbic acid, dopamine, and uric acid). This type of pretreated SPCE successfully enhances the electrooxidation current and overcomes the interference effects and clearly exhibits the signals for the propofol detection using cyclic voltammetry and flow injection analysis techniques. The preanodized SPCE shows the electrooxidation signals for the propofol detection in the linear range of 0.09 to 0.90 μM, respectively. Further, the sensitivity of the proposed electrode for the propofol detection is found to be 3.6 μA μM−1.

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Acknowledgment

This work was supported by grants from National Science Council (NSC) of Taiwan (ROC).

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Authors and Affiliations

  1. Electroanalysis and Bioelectrochemistry Lab, Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, No.1, Section 3, Chung-Hsiao East Road, Taipei, 106, Taiwan, Republic of China

    Soundappan Thiagarajan, Ching-Yi Cheng, Shen-Ming Chen & Tsung-Hsuan Tsai

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  1. Soundappan Thiagarajan
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  2. Ching-Yi Cheng
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  3. Shen-Ming Chen
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  4. Tsung-Hsuan Tsai
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Correspondence to Shen-Ming Chen.

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Thiagarajan, S., Cheng, CY., Chen, SM. et al. Electrochemical detection of propofol at the preanodized carbon electrode. J Solid State Electrochem 15, 781–786 (2011). https://doi.org/10.1007/s10008-010-1160-3

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  • DOI: https://doi.org/10.1007/s10008-010-1160-3

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