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Implants placed into alveoli with periapical lesions: an experimental study in dogs

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Oral and Maxillofacial Surgery Aims and scope Submit manuscript

Abstract

Objective

To histologically analyze the effect of a curettage of the granulation tissue on healing at implants installed immediately after the extraction of teeth presenting periapical lesions.

Material and methods

In seven dogs, the dental pulp was removed from the pulp chamber and from the root canals of the right and left third and the fourth mandibular premolars and of the left second premolar. The chambers were left opened and, after 3 months, apical lesions were present, and the premolars were extracted. One alveolus each premolar was selected and, before implant installation, the apical lesions of two alveoli were curetted (curettage group) while the other three were not treated (no-treatment group). The second right premolar was also extracted (Negative control group). Six implants each dog were installed, and a fully submerged healing was allowed. Four months after, biopsies were collected, and histological analyses were performed.

Results

The proportions of new bone at the entire body of the implant was 70.2 ± 10.7% at the no-treatment group, 72.1 ± 14.8% at the curettage group, and 69.6 ± 3.7% at the negative control group. The respective new bone proportion at the apical aspect of the implants was 68.4 ± 17.5%, 61.5 ± 27.3%, and 78.1 ± 5.7%. None of the differences among the various groups were statistically significant. No inflammatory infiltrates were seen in the apical region.

Conclusions

In this experimental study, it is concluded that the removal of the granulation tissue seems not to be necessary to obtain a proper osseointegration of implants installed immediately after the extraction of teeth presenting a periapical lesion.

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Acknowledgments

The authors thank Dr. Karol Alí Apaza Alccayhuaman (KAAA) for the time spent for the radiographic measurements.

Funding

The experiment was economically supported by Sweden & Martina, Due Carrare, PD, Italy, and by ARDEC Academy, Rimini, Italy. The implants were provided free of charge by Sweden & Martina.

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Authors and Affiliations

  1. ARDEC Academy, Viale Giovanni Pascoli, 67, Rimini, Italy

    Massimiliano Rea, Ermenegildo Federico De Rossi, Tomaso Mainetti & Daniele Botticelli

  2. Faculty of Dentistry, University of Medical Science, La Habana, Cuba

    Franco Bengazi & Joaquin Urbizo Velez

  3. Fundación ARDEC, Cartagena de Indias, Colombia

    Daniele Botticelli

Authors
  1. Massimiliano Rea
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  2. Franco Bengazi
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  3. Joaquin Urbizo Velez
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  4. Ermenegildo Federico De Rossi
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  5. Tomaso Mainetti
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  6. Daniele Botticelli
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Corresponding author

Correspondence to Daniele Botticelli.

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The authors declare that they have no conflict of interest.

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All applicable international, national, and/or institutional guidelines for the care and use of animals were followed.

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This article does not contain any studies with human participants

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Rea, M., Bengazi, F., Velez, J.U. et al. Implants placed into alveoli with periapical lesions: an experimental study in dogs. Oral Maxillofac Surg 25, 351–357 (2021). https://doi.org/10.1007/s10006-020-00926-8

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  • DOI: https://doi.org/10.1007/s10006-020-00926-8

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