Skip to main content

Advertisement

SpringerLink
Log in

A new case of the pilomatrixoma rare in the preauricular region and review of series of cases

  • Case Report
  • Published:
Oral and Maxillofacial Surgery Aims and scope Submit manuscript

Abstract

Pilomatrixoma is considered a rare benign tumor arising from the hair follicle, most common in the head and neck region, but it is rarely diagnosed on a clinical basis. This report describes a new case of giant pilomatrixoma in a 36-year-old female patient. The nodule was localized in the preauricular area on the right side, appearing as a slow-growing, fixed, painless, with a hardened consistency, unusual giant (4.5 cm). A cone-beam computed tomography (CBCT) examination showed a slightly hyperdense lesion, and fine-needle aspiration cytology (FNAC) revealed peripheral blood and mononucleated inflammatory cells. After enucleation of lesion, a diagnosis of pilomatrixoma was confirmed. The differential diagnosis of pilomatrixoma is broad, because its characteristics also can be found in other lesions common to the head and neck. Thus, a lesion in the head and neck, adherent to the skin, and well demarcated, mainly in the young and in females, should be suspected as pilomatrixoma.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

Explore related subjects

Discover the latest articles, news and stories from top researchers in related subjects.

References

  1. Lee KH, Kim HJ, Suh CH (2000) Pilomatricoma in the head and neck: CT findings in three patients. J Comput Assist Tomogr 24:332–335

    Article  CAS  Google Scholar 

  2. Sinhasan SP, Jadhav CR, Bhat RV, Amaranathan A (2013) Pilomatrixoma - presented as hypopigmented tender nodule: diagnosed by FNAC: a case report with review of literature. Indian J Dermatol 58:405

    Article  Google Scholar 

  3. Zloto O, Fabian ID, Vishnevskia Dai V, Ben Simon GJ, Rosner M (2015) Periocular pilomatrixoma: a retrospective analysis of 16 cases. Ophthal Plast Reconstr Surg 31:19–22

    Article  Google Scholar 

  4. Makek M, Franklin DJ, Fisch U (1989) Preauricular pilomatrixoma: a diagnostic pitfall. Oral Surg Oral Med Oral Pathol 68:451–454

    Article  CAS  Google Scholar 

  5. Malherbe A, Chenantais J (1880) Note surl’epitheliome calcifit: desglandes sebaces. Progr Med 8:826–828

    Google Scholar 

  6. De Rosa DC, Lin-Hurtubise K (2012) Pilomatricoma: an un usual dermatologic neoplasm. Hawaii J Med Public Health 71:282–286

    Google Scholar 

  7. Lever WF, Griesemer RD (1949) Calcifying epithelioma of Malherbe; report of 15 cases, with comments on its differentiation from calcified epidermal cyst and on its histogenesis. Arch Dermatol Syphilol 59:506–518

    Article  CAS  Google Scholar 

  8. Forbis R Jr, Helwig EB (1961) Pilomatrixoma (calcifying epithelioma). Arch Dermatol 83:606–618

    Article  Google Scholar 

  9. Souto MP, Matsushita MM, Matsushita GM, Souto LR (2013) An unusual presentation of giant pilomatrixoma in an adult patient. J Dermatol Case Rep 7:56–59

    Article  Google Scholar 

  10. Whittemore KR, Cohen M (2012) Imaging and review of a large pre-auricular pilomatrixoma in a child. World J Radiol 4:228–230

    Article  Google Scholar 

  11. Cappellesso R, Bellan A, Saraggi D, Salmaso R, Ventura L, Fassina A (2015) YAP immunoreactivity is directly related to pilomatrixoma size and proliferation rate. Arch Dermatol Res 307:379–383

    Article  CAS  Google Scholar 

  12. Rachakonda T, Kacker A, Koizumi J (2010) Pediatric pilomatrixoma of the preauricular region. Acta Cytol 54:724–726

    Article  Google Scholar 

  13. Yoshimura Y, Obara S, Mikami T, Matsuda S (1997) Calcifying epithelioma (pilomatrixoma) of the head and neck: analysis of 37 cases. Br J Oral Maxillofac Surg 35:429–432

    Article  CAS  Google Scholar 

  14. Williams CM, Bozner P, Oliveri CV, Horenstein MG (2003) Melanocytic matricoma: case confirmation of a recently described entity. J Cutan Pathol 30:275–278

    Article  Google Scholar 

  15. Vidyalakshmi S, Aravindhan R (2014) Adenoid cystic carcinoma of the buccal mucosa: a case report with review of literature. J Clin Diagn Res 8:266–268

    Google Scholar 

  16. Aydin S, Bilmez ZE, Erdogdu S, Altintoprak N, Kayipmaz S (2016) Complicate giant pilomatrixoma of the parotid region. J Maxillofac Oral Surg 15:111–115

    Article  Google Scholar 

  17. Sciandra D, Dispenza F, Porcasi R, Kulamarva G, Saraniti C (2008) Pleomorphic adenoma of the lateral nasal wall: case report. Acta Otorhinolaryngol Ital 28:150–153

    CAS  PubMed  PubMed Central  Google Scholar 

  18. Vicente OP, Marqués NA, Aytés LB, Gay Escoda C (2008) Minor salivary gland tumors: a clinicopathological study of 18 cases. Med Oral Patol Oral Cir Bucal 13:E582–E588

    Google Scholar 

  19. Just T, Hingst V, Kreutzer HJ, Pau HW (2005) Hard, expanding preauricular swelling in a 6-year-old child. HNO 53:1074–1076

    Article  CAS  Google Scholar 

  20. Bernier FE, Schreiber A, Coulombe J, Hatami A, Marcoux D (2017) Pilomatricoma associated with kabuki syndrome. Pediatr Dermatol 34:e26–e27

    Article  Google Scholar 

  21. Bajpai M, Arora M, Chandolia B (2016) A rare case of pilomatrixoma (calcifying epithelioma of Malherbe) of parotid space masquerading as salivary gland tumor. Iran J Pathol 11:418–420

    PubMed  PubMed Central  Google Scholar 

  22. Dutta M, Chatterjee I (2016) A lesson learnt: retrospection in a case of pilomatricoma mimicking as parotid neoplasm. Einstein (Sao Paulo) 14:104–105

    Article  Google Scholar 

  23. Bellafiore S, Tagliavini E, Carlinfante G, Piana S (2016) Pilomatrixoma is a diagnostic trap in fine-needle aspiration cytology of the parotid region. Diagn Cytopathol 44:516–518

    Article  Google Scholar 

  24. Bhatt MK, Sommerville R, Ravi Kumar AS (2012) FDG PET/CT appearance of benign pilomatricoma. Clin Nucl Med 37:684–686

    Article  Google Scholar 

  25. Hwang JY, Lee SW, Lee SM (2005) The common ultrasonographic features of pilomatricoma. J Ultrasound Med 24:1397–1402

    Article  Google Scholar 

  26. Yuca K, Kutluhan A, Cankaya H, Akman E (2004) Giant pilomatrixoma arising in the preauricular region: a case report. Kulak Burun Bogaz Ihtis Derg 12:147–149

    PubMed  Google Scholar 

  27. Silva TA, Moraes EF Jr, Consolaro A, Lara VS (2003) Pilomatricoma of the auricular region: case report. Braz Dent J 14:223–226

    Article  Google Scholar 

  28. Sari A, Yavuzer R, Isik I, Latifoglu O, Ataoglu O (2002) Atypical presentation of pilomatricoma: a case report. Dermatol Surg 28:603–605

    PubMed  Google Scholar 

  29. Phyu KK, Bradley PJ (2001) Pilomatrixoma in the parotid region. Laryngol Otol 115:1026–1028

    CAS  Google Scholar 

  30. Ooi LL, Sim CS, Soo KC (1992) Calcifying epithelioma of Malherbe--a case report of a large preauricular tumour. Ann Acad Med Singap 21:379–381

    CAS  PubMed  Google Scholar 

  31. Yoshimura Y, Oka M (1990) Pilomatrixoma of the preauricular region. Br J Oral Maxillofac Surg 28:416–418

    Article  CAS  Google Scholar 

  32. Cianga CM, Cianga P, Dumitrescu GF, Sava A (2016) IL-8, IL-8RA (CXCR1) and IL-8RB (CXCR2) expression in pilomatricoma. Romanian J Morphol Embryol 57:59–64

    Google Scholar 

Download references

Acknowledgements

Special thanks to Professor Brad Neville for the English stile review and advise during the diagnostic process.

Author information

Authors and Affiliations

  1. Oral Pathology and Oral Medicine, Amazonas State University, Manaus, AM, 69050-010, Brazil

    Tiago Novaes Pinheiro

  2. Maxilofacial Surgery, Amazonas State University, Manaus, AM, 69050-010, Brazil

    Flavio Têndolo Fayad

  3. Maxilofacial Surgery, Amazonas State University Maxilofacial Surgery Residency, Manaus, AM, 69050-010, Brazil

    Pedro Arantes

  4. Endodontics, School of Dentistry, São Paulo State University (Unesp), Araçatuba, SP, 16015-050, Brazil

    Francine Benetti & Luciano Tavares Angelo Cintra

  5. Periodontics, School of Dentistry, University Center São Lucas, Porto Velho, RO, 76804- 295, Brazil

    Gustav Guimarães

Authors
  1. Tiago Novaes Pinheiro
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Flavio Têndolo Fayad
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Pedro Arantes
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Francine Benetti
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Gustav Guimarães
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Luciano Tavares Angelo Cintra
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Luciano Tavares Angelo Cintra.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Informed consent

The consent of patient was obtained for publication of this case report and images.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Pinheiro, T.N., Fayad, F.T., Arantes, P. et al. A new case of the pilomatrixoma rare in the preauricular region and review of series of cases. Oral Maxillofac Surg 22, 483–488 (2018). https://doi.org/10.1007/s10006-018-0724-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10006-018-0724-8

Keywords

Search

Navigation