Oral and Maxillofacial Surgery

, Volume 22, Issue 4, pp 483–488 | Cite as

A new case of the pilomatrixoma rare in the preauricular region and review of series of cases

  • Tiago Novaes Pinheiro
  • Flavio Têndolo Fayad
  • Pedro Arantes
  • Francine Benetti
  • Gustav Guimarães
  • Luciano Tavares Angelo CintraEmail author
Case Report


Pilomatrixoma is considered a rare benign tumor arising from the hair follicle, most common in the head and neck region, but it is rarely diagnosed on a clinical basis. This report describes a new case of giant pilomatrixoma in a 36-year-old female patient. The nodule was localized in the preauricular area on the right side, appearing as a slow-growing, fixed, painless, with a hardened consistency, unusual giant (4.5 cm). A cone-beam computed tomography (CBCT) examination showed a slightly hyperdense lesion, and fine-needle aspiration cytology (FNAC) revealed peripheral blood and mononucleated inflammatory cells. After enucleation of lesion, a diagnosis of pilomatrixoma was confirmed. The differential diagnosis of pilomatrixoma is broad, because its characteristics also can be found in other lesions common to the head and neck. Thus, a lesion in the head and neck, adherent to the skin, and well demarcated, mainly in the young and in females, should be suspected as pilomatrixoma.


Pilomatrixoma Pilomatricoma Calcifying epithelioma of Malherbe Head and neck Skin 



Special thanks to Professor Brad Neville for the English stile review and advise during the diagnostic process.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Informed consent

The consent of patient was obtained for publication of this case report and images.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Tiago Novaes Pinheiro
    • 1
  • Flavio Têndolo Fayad
    • 2
  • Pedro Arantes
    • 3
  • Francine Benetti
    • 4
  • Gustav Guimarães
    • 5
  • Luciano Tavares Angelo Cintra
    • 4
    Email author
  1. 1.Oral Pathology and Oral MedicineAmazonas State UniversityManausBrazil
  2. 2.Maxilofacial SurgeryAmazonas State UniversityManausBrazil
  3. 3.Maxilofacial SurgeryAmazonas State University Maxilofacial Surgery ResidencyManausBrazil
  4. 4.Endodontics, School of DentistrySão Paulo State University (Unesp)AraçatubaBrazil
  5. 5.Periodontics, School of Dentistry, University Center São LucasPorto VelhoBrazil

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