Oral and Maxillofacial Surgery

, Volume 22, Issue 2, pp 193–196 | Cite as

Prevalence of the systemic inflammatory response syndrome in patients who underwent orthognathic surgery

  • Magno Liberato Silva
  • Andréia Ferreira Ribeiro
  • Fábio Ricardo Loureiro Sato
  • Roger William Fernandes Moreira
Original Article



The systemic inflammatory response syndrome (SIRS) is the body’s response to an insult, such as infection, trauma, burn, and surgical stress linked to several factors deemed potential for multiple organ failure if left untreated. Thus, the aim of this paper was a prospective study to examine the incidence of SIRS in postoperative patients who underwent orthognathic surgery from June/2013 to July/2016.


The sample consisted of 80 patients who underwent bimaxillary orthognathic surgery, with data on vital signs and white blood cell count collected preoperatively, and the same data collected in the immediate postoperative period, in addition to CO2 pressure in arterial blood by blood gas analysis. The data were tabulated and cases of SIRS (2 or more signs out of four pre-set signs) were identified within 24 h after surgery.


From the sample of 80 patients, 26 (32.5% of total) patients had SIRS with higher incidence in females who are 40 years old.


The incidence of patients who develop SIRS after orthognathic surgery is relatively high and we should pay attention to the possible complications that these cases can evolve.


Systemic inflammatory response syndrome Orthognathic surgery Sepsis Septic shock 


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Magno Liberato Silva
    • 1
  • Andréia Ferreira Ribeiro
    • 2
  • Fábio Ricardo Loureiro Sato
    • 3
  • Roger William Fernandes Moreira
    • 4
  1. 1.Resident of Oral and Maxillofacial SurgeryBrazilian Red Cross HospitalSão PauloBrazil
  2. 2.Oral and Maxillofacial SurgeonBrazilian Red Cross HospitalSão PauloBrazil
  3. 3.College of Dentistry, São José dos Campos and Oral and Maxillofacial Surgeon, Oral and Maxillofacial Surgery AreaState University of São Paulo – UNESPSão PauloBrazil
  4. 4.Chief of Oral and Maxillofacial Surgery DepartmentBrazilian Red Cross HospitalSão PauloBrazil

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